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Table 1 Association of mRNA expression with LUAD patient tobacco smoking history in the TCGA database

From: Identification and validation of smoking-related genes in lung adenocarcinoma using an in vitro carcinogenesis model and bioinformatics analysis

Smoking history Cases GYPC NME1 SLIT2
(N) (log2(RSEM+1)) (log2(RSEM+1)) (log2(RSEM+1))
1 75 8.64  ±  0.93 10.64  ±  0.98 7.85  ±  1.43
2 119 8.20  ±  1.00** 11.06  ±  0.70** 7.17  ±  1.53**
3 135 8.39  ±  0.82 10.62  ±  0.91## 7.69  ±  1.50##
4 168 8.47  ±  0.92# 10.99  ±  0.80** 7.54  ±  1.55#
  1. 1 = Lifelong Non-smokers (less than 100 cigarettes smoked in Lifetime), 2 = Current smokers (includes daily smokers and non-daily smokers or occasional smokers), 3 = Current reformed smokers for >15 years (greater than 15 years), 4 = Current reformed smokers for \(\le \)15 years (less than or equal to 15 years). Data represented are Mean ± SD, n depend on how many valid LUAD samples with corresponding factors. SD indicates standard deviation. *p < 0.05, versus Lifelong Non-smokers; **p < 0.01, versus Current smokers; #p < 0.05, versus Lifelong Non-smokers; ##p < 0.01, versus Current smokers