Convective forces increase rostral delivery of intrathecal radiotracers and antisense oligonucleotides in the cynomolgus monkey nervous system

Table 3 P values for Tukey’s multiple comparisons test for Malat1 RNA expression results

Comparison	Adjusted P value
Comparison	Lumbar spinal cord	Thoracic spinal cord	Cervical spinal cord	Frontal cortex
Naive vs. low volume no wrap	< 0.0001*	< 0.0001*	0.0008*	0.463
Naive vs. low volume + wrap	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*
Naive vs. high volume no wrap	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*
Naive vs. high volume + wrap	< 0.0001*	< 0.0001*	< 0.0001*	< 0.0001*
Low volume no wrap vs. high volume no wrap	0.9877	0.9916	0.6978	0.0018*
Low volume no wrap vs. low volume + wrap	0.9731	0.9976	0.9477	0.0014*
High volume no wrap vs. high volume + wrap	> 0.9999	> 0.9999	> 0.9999	0.9086

ISSN: 1479-5876