Table 1 Whole body CSF volume determined in cynomolgus monkeys using MRI image analysis
Animal # | Sex | Body weight (kg) | Total CSF volume (cm3) |
|---|---|---|---|
A1001 | Male | 3.7 | 14.4 |
A1002 | Female | 3.1 | 8.8 |
A1003 | Male | 3.3 | 11.0 |
A1004 | Female | 3.3 | 10.0 |
A1005 | Male | 3.7 | 10.3 |
A1006 | Female | 4.1 | 11.8 |
A1007 | Female | 3.8 | 11.9 |
A1008 | Male | 4.2 | 11.7 |
A1009 | Female | 3.1 | 12.6 |
A1010 | Male | 3.4 | 12.4 |
A1011 | Female | 2.8 | 10.4 |
A1012 | Male | 3.7 | 13.2 |
A1013 | Female | 3.2 | 10.6 |
A1014 | Male | 3.1 | 10.4 |
A1015 | Female | 4.0 | 12.3 |
A1016 | Male | 4.2 | 11.1 |
A1017 | Female | 4.1 | 10.9 |
A1018 | Male | 3.2 | 11.5 |
A1019 | Male | 4.3 | 14.9 |
A1020 | Female | 3.4 | 11.0 |
Analysis of total CSF volume (cm3) | |||
|---|---|---|---|
Parameter | All animals | Female | Male |
Mean | 11.6 | 11.0 | 12.1 |
SD | 1.5 | 1.1 | 1.6 |
CV% | 12.7% | 10.4% | 13.3% |
Median | 11.3 | 10.9 | 11.6 |
Max | 14.9 | 12.6 | 14.9 |
Min | 8.8 | 8.8 | 10.3 |
Range | 8.8–14.9 | 8.8–12.6 | 10.3–14.9 |
Female vs. male T-test P value | 0.1043 | ||