Table 2 Univariate and multivariate cox analyses in gliomas in TCGA
From: Clinical characterization, genetic profiling, and immune infiltration of TOX in diffuse gliomas
Factor | TCGA RNA-seq set | |||||
|---|---|---|---|---|---|---|
Univariate | Multivariate | |||||
P | HR | 95% CI | P | HR | 95% CI | |
TOX | ||||||
 High vs. low | < 0.001 | 4.32 | 3.24–5.77 | 0.044 | 1.47 | 1.01–2.14 |
Age | ||||||
 Increasing years | < 0.001 | 1.06 | 1.05–1.07 | < 0.001 | 1.03 | 1.02–1.04 |
Gender | ||||||
 Male vs. Female | 0.084 | 1.26 | 0.97–1.63 | 0.229 | 1.20 | 0.90–1.56 |
WHO grade | ||||||
 Grade III vs. II | < 0.001 | 3.34 | 2.28–4.89 | < 0.001 | 2.20 | 1.48–3.26 |
 Grade IV vs. II | < 0.001 | 17.95 | 12.11–26.59 | <  0.001 | 3.64 | 2.23–5.95 |
1p19q status | ||||||
 Codel vs. Non-codel | < 0.001 | 4.23 | 2.75–6.51 | 0.012 | 1.88 | 1.15–3.10 |
IDH status | ||||||
 Mutation vs. wild-type | < 0.001 | 8.92 | 6.76–11.75 | < 0.001 | 2.27 | 1.47–3.51 |