Skip to main content

Table 2 Univariate and multivariate cox analyses in gliomas in TCGA

From: Clinical characterization, genetic profiling, and immune infiltration of TOX in diffuse gliomas

Factor TCGA RNA-seq set
Univariate Multivariate
P HR 95% CI P HR 95% CI
TOX
 High vs. low < 0.001 4.32 3.24–5.77 0.044 1.47 1.01–2.14
Age
 Increasing years < 0.001 1.06 1.05–1.07 < 0.001 1.03 1.02–1.04
Gender
 Male vs. Female 0.084 1.26 0.97–1.63 0.229 1.20 0.90–1.56
WHO grade
 Grade III vs. II < 0.001 3.34 2.28–4.89 < 0.001 2.20 1.48–3.26
 Grade IV vs. II < 0.001 17.95 12.11–26.59 <  0.001 3.64 2.23–5.95
1p19q status
 Codel vs. Non-codel < 0.001 4.23 2.75–6.51 0.012 1.88 1.15–3.10
IDH status
 Mutation vs. wild-type < 0.001 8.92 6.76–11.75 < 0.001 2.27 1.47–3.51