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Table 4 Preliminary targeted panel—immunology relevance focus

From: A modular framework for the development of targeted Covid-19 blood transcript profiling panels

Module set Module ID NCBI
Entrez ID
Symbol Name Module set functional annotation
A1/S1 M15.38 916 CD3E CD3e molecule T cells
A1/S2 M14.49 974 CD79B CD79b molecule Gene transcription
A1/S3 M14.80 3122 HLA-DRA Major histocompatibility complex, class II, DR alpha B cells
A2/S1 M9.1 3002 GZMB Granzyme B Cytotoxic lymphocytes
A2/S2 M13.13 4282 MIF Macrophage migration inhibitory factor TBD
A4/S1 M16.77 3811 KIR3DL1 Killer cell immunoglobulin like receptor, three Ig domains and long cytoplasmic tail 1 Antigen presentation
A5/S1 M16.95 972 CD74 CD74 molecule B cells
A5/S2 M16.111 27242 TNFRSF21 TNF receptor superfamily member 21 B cells
A7/S1 M15.61 23166 STAB 1 Stabilin 1 Monocytes
A8/S1 M16.30 3600 IL15 Interleukin 15 Complement
A8/S2 M16.106 57823 SLAMF7 SLAM family member 7 TBD
A10/S1 M15.102 246 ALOX15 Arachidonate 15-lipoxygenase Prostanoids
A26/S1 M12.2 942 CD86 CD86 molecule Monocytes
A27/S1 M12.15 608 CD38 CD38 molecule Cell cycle
A28/S1 M8.3 9636 ISG15 ISG15 ubiquitin like modifier Interferon response
A28/S2 M15.64 10475 TRIM38 Tripartite motif containing 38 Interferon response
A28/S3 M10.1 115362 GBP5 Guanylate binding protein 5 Interferon response
A31/S1 M16.64 1950 EGF Epidermal growth factor Platelet/prostaglandin
A31/S2 M15.58 2214 FCGR3A Fc fragment of IgG receptor IIIa Monocytes
A33/S1 M14.24 91 ACVR1B Activin A receptor type 1B Cytokines/chemokines, Inflammation
A33/S2 M14.19 23765 IL17RA Interleukin 17 receptor A Inflammation
A34/S1 M8.2 3674 ITGA2B Integrin subunit alpha 2b Platelets, prostanoids
A35/S1 M13.3 1241 LTB4R Leukotriene B4 receptor Inflammation
A35/S2 M12.10 51311 TLR8 Toll like receptor 8 Neutrophils, inflammation
A36/S1 M16.34 2993 GYPA Glycophorin A (MNS blood group) Gene transcription
A37/S1 M11.3 2623 GATA1 GATA binding protein 1 Erythroid cells
A38/S1 M10.4 4057 LTF Lactotransferrin Neutrophil activation
A38/S2 M16.96 56729 RETN Resistin Erythroid cells
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