Table 4 Top reversing drugs against the MA15 (Mouse model of SARS-CoV) gene expression signature based on DCT
Drug Name | Concentration (uM) | Time (h) | DCT Score | p-value | Adjusted p-value |
|---|---|---|---|---|---|
vitamin e | 10 | 6 | − 0.0744254 | < 1.00E−05 | < 1.00E−05 |
chembl2179387 | 0.04 | 24 | − 0.0620614 | < 1.00E−05 | < 1.00E−05 |
ruxolitinib | 3 | 24 | − 0.060335 | < 1.00E−05 | < 1.00E−05 |
chembl1235119 | 3 | 24 | − 0.0595284 | < 1.00E−05 | < 1.00E−05 |
cinnarizine | 0.1 | 24 | − 0.0565905 | < 1.00E−05 | < 1.00E−05 |
glutamine | 1 | 6 | − 0.0556337 | < 1.00E−05 | < 1.00E−05 |