Table 1 Clinical and tumor characteristics of training and validation cohort
Variables | Training cohort (n = 1052) | Validation cohort (n = 114) | ||||
|---|---|---|---|---|---|---|
No. (%) | No. (%) | |||||
Lobe- | Sublob- | Pneumo- | Lobe- | Sublob- | Pneumo- | |
Sex | ||||||
Male | 282 (44.5) | 167 (43. 7) | 15 (41.7) | 52 (66.7) | 7 (77.8) | 19 (70.4) |
Female | 352 (55.5) | 215 (56.3) | 21 (58.3) | 26 (33.3) | 2 (22.2) | 8 (29.6) |
Age | ||||||
≤ 60 | 169 (26.7) | 99 (25.9) | 16 (44.5) | 41 (52.5) | 5 (55.6) | 22 (81.5) |
60–70 | 257 (40.5) | 130 (34.0) | 12 (33.3) | 30 (38.5) | 3 (33.3) | 5 (18.5) |
> 70 | 208 (32.8) | 153 (40.1) | 8 (22.2) | 7 (9.0) | 1 (11.1) | 0 (0.0) |
Marital | ||||||
Unmarried | 287 (45.3) | 167 (43.7) | 11 (30.6) | – | – | – |
Married | 347 (54.7) | 215 (56.3) | 25 (69.4) | – | – | – |
Lateral | ||||||
Left | 282 (44.5) | 175 (45.8) | 23 (63.9) | 38 (48.7) | 3 (33.3) | 22 (81.5) |
Right | 352 (55.5) | 207 (54.2) | 13 (36.1) | 40 (51.3) | 6 (66.7) | 5 (18.5) |
Primary site | ||||||
Upper lobe | 377 (59.5) | 235 (61.5) | 18 (50.0) | 32 (41.0) | 6 (66.7) | 6 (22.2) |
Lower lobe | 202 (31.8) | 90 (23.6) | 7 (19.4) | 34 (43.6) | 2 (22.2) | 6 (22.2) |
Other | 55 (8.7) | 57 (14.9) | 11 (30.6) | 12 (15.4) | 1 (11.1) | 15 (55.6) |
Grade | ||||||
I–II | 30 (4.7) | 14 (3.7) | 4 (11.1) | – | – | – |
III | 227 (35.8) | 107 (28.0) | 9 (25.0) | – | – | – |
IV | 191 (30.1) | 97 (25.4) | 13 (36.1) | – | – | – |
Unknown | 186 (29.4) | 164 (42.9) | 10 (27.8) | – | – | – |
T stage | ||||||
T1 | 326 (51.4) | 197 (51.6) | 5 (13.9) | 26 (33.3) | 3 (33.3) | 1 (3.7) |
T2 | 231 (36.4) | 107 (28.0) | 10 (27.8) | 29 (37.2) | 4 (44.5) | 6 (22.2) |
T3–T4 | 77 (12.2) | 78 (20.4) | 21 (58.3) | 23 (29.5) | 2 (22.2) | 20 (74.1) |
N stage | ||||||
N0 | 387 (61.0) | 229 (59.9) | 11 (30.6) | 25 (32.1) | 3 (33.3) | 4 (14.8) |
N1 | 142 (22.4) | 43 (11.3) | 15 (41.7) | 21 (26.9) | 3 (33.3) | 7 (25.9) |
N2 | 105 (16.6) | 110 (28.8) | 10 (27.8) | 32 (41.0) | 3 (33.3) | 16 (59.3) |
LNR | ||||||
< 0.01 | 379 (59.8) | 125 (32.7) | 11 (30.6) | 23 (29.5) | 2 (22.2) | 3 (11.1) |
> 0.01 | 235 (37.0) | 98 (25.7) | 21 (58.3) | 54 (69.2) | 6 (66.7) | 23 (85.2) |
NO* | 20 (3.2) | 159 (41.6) | 4 (11.1) | 1 (1.3) | 1 (11.1) | 1 (3.7) |
Radiation | ||||||
No | 412 (65.0) | 206 (53.9) | 22 (61.1) | 55 (70.5) | 5 (55.6) | 23 (85.2) |
Yes | 222 (35.0) | 176 (46.1) | 14 (38.9) | 23 (29.5) | 4 (44.4) | 4 (14.8) |
Chemo | ||||||
No | 201 (31.7) | 117 (30.6) | 13 (36.1) | 18 (23.1) | 2 (22.2) | 10 (37.0) |
Yes | 433 (62.3) | 265 (69.4) | 23 (63.9) | 60 (76.9) | 7 (77.8) | 17 (63.0) |