|
Characteristics
|
Oral mucositis
|
P
|
OR
|
95% CI
|
|---|
|
Grade ≥ 3
|
Grade ≤ 2
|
|---|
|
Number of patients
|
349 (23.79%)
|
1118 (76.21%)
| | | |
|
Age (Mean ± SD)
|
45.12 ± 10.71
|
45.18 ± 10.94
|
0.934
|
1.00
|
0.99–1.01
|
|
Gender
|
0.524
| | |
|
Male
|
258
|
807
| |
–
|
–
|
|
Female
|
91
|
311
| |
0.92
|
0.69–1.20
|
|
Clinical stage
|
0.047
| | |
|
I–II
|
71
|
286
| |
–
|
–
|
|
III–IV
|
278
|
832
| |
1.35
|
1.00–1.81
|
|
Tumor stagea
|
0.035
| | |
|
1–2
|
85
|
338
| |
–
|
–
|
|
3–4
|
264
|
780
| |
1.35
|
1.02–1.77
|
|
Radiation technique
|
< 0.001
| | |
|
2D-CRT
|
112
|
641
| |
–
|
–
|
|
IMRT
|
237
|
477
| |
2.84
|
2.21–3.67
|
|
Treatment scheme
|
< 0.001
| | |
|
RT alone
|
24
|
325
| |
–
|
–
|
|
RT + IC/AC
|
15
|
190
|
0.845
|
1.07
|
0.55–2.09
|
|
CCRT
|
310
|
603
|
< 0.001
|
6.96
|
4.50–10.77
|
- 95% CI, 95% confidence interval; SD, standard deviation; 2D-CRT, two-dimensional conventional radiotherapy; IMRT, intensity modulated radiation therapy; RT, radiotherapy; RT + IC/AC, Radiotherapy with induction chemotherapy and/or adjuvant chemotherapy; CCRT, Concurrent chemoradiotherapy
- aThe patients were staged according to the 2009 7th UICC/AJCC staging system
