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Fig. 2 | Journal of Translational Medicine

Fig. 2

From: Accumulation of blood-circulating PD-L1-expressing M-MDSCs and monocytes/macrophages in pretreatment ovarian cancer patients is associated with soluble PD-L1

Fig. 2

Parallel evaluation of HLA-DR−/lowCD14+ monocytic myeloid-derived suppressor cells (M-MDSCs) and HLA-DR+CD14+ monocytes/macrophages (MO/MA) in ovarian cancer patients with different clinicopathologic characteristics. ad Samples from the blood (n = 43), ascites (n = 26) and tumour tissue (n = 29) of patients with different stage, grade, Kurman–Shih types and histology types of OC. Blood samples from healthy women were also examined (n = 15). The frequency of M-MDSCs and MO/MA is shown as the percentage of mononuclear cells (MCs). The horizontal lines represent the median values and the whiskers indicate the minimum and maximum values. Each point represents an individual patient. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001

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