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Table 1 Response rates to EBV and HCMV T-activated proteins and peptide pools

From: Evaluation of T-activated proteins as recall antigens to monitor Epstein–Barr virus and human cytomegalovirus-specific T cells in a clinical trial setting

Antigen PBMC specimen T-cell population TP-induced reactivity (%)a PP-induced reactivity (%)a
EBV-BZLF1 Fresh CD4 87 77
Cryo 77 70
Fresh CD8 73 80
Cryo 67 87
EBV-EBNA3A Fresh CD4 73 87
Cryo 87 77
Fresh CD8 90 87
Cryo 80 77
HCMV-IE1 Fresh CD4 94 89
Cryo 83 83
Fresh CD8 94 100
Cryo 72 94
HCMV-pp65 Fresh CD4 95 100
Cryo 95 100
Fresh CD8 95 95
Cryo 74 100
  1. aReactivity defines the percentage of reactive donors after stimulation of freshly or cryopreserved PBMC of EBV- and HCMV-seropositive donors with the respective antigens