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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Decidual CD8+T cells exhibit both residency and tolerance signatures modulated by decidual stromal cells

Fig. 5

Upregulation of CD103 by decidual stromal cells and effector molecule expression in CD103+dT cells. a Representative FACS plots and percentages of expression of CD69 + CD103 + cells in CD8+pT cells and CD8+dT cells. Percentages of CD69 + CD103+ cells are depicted within four subpopulations of CD8+Tcell; b CD103 expression of CD8+pT cells cocultured with DSCs and trophoblasts, respectively, for three days and analyzed by flow cytometry; c Representative FACS plots (Left) and percentages (Right) of the expression of intracellular granzyme B and IFN-γ in CD103+ and CD103 − CD8+dT cells stimulated for 6 h with PMA/Ionomycin (1 μg/mL). Graphs show the data of six to ten samples in each group; a paired t-test was used to calculate the p-values, *p = < 0.05, ***p = < 0.005, ****p = < 0.0001. CD103 expression of CD8+pT cells cocultured with DSCs and trophoblasts, respectively, for three days and analyzed by flow cytometry. Graphs show the data of six samples in each group; a paired t-test was used to calculate the p-values, *p = < 0.05, **p = < 0.01

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