Fig. 4
Secondary analysis showed decrease in CD3 + T-cell density. a CD3 plot Boxplot and scatter plot for CD3 density (Treated vs. Control), p = 0.995 for Welch two sample t-test comparing CD3+ T-cell density of Tumor in treated group and historic control group, i.e. the mean CD3+ T-cell density in tumor was significantly lower in treated subjects compared to historical control subjects. Mean CD3+ T-cell density in the tumor region of the Rituximab-treated group was 0.0223 mm2/mm2 (95% CI 0.0116, 0.033) and 0.0419 mm2/mm2 (95% CI 0.0305, 0.0533) in the control group. b Within subject difference of CD3 density: tumor minus adjacent normal tissue (Treated vs. Controls)