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Table 2 Linear regression analysis between SBP trajectory groups and indicators of kidney disease in 2016

From: Unstably controlled systolic blood pressure trajectories are associated with markers for kidney damage in prediabetic population: results from the INDEED cohort study

 

Group 1

Group 2

Group 3

Group 4

Group 5

N (%)

726 (50.3%)

323 (22.3%)

176 (12.1%)

181 (12.5%)

45 (2.8%)

eGFR (n = 1451)

 Model 1

− 2.75*

1.00

− 8.90*

− 7.62*

− 13.85*

 Model 2

0.96

1.00

− 1.66

− 1.19

− 4.81*

 Model 3

0.99

1.00

− 1.61

− 1.13

− 4.70*

 Model 4

0.84

1.00

− 1.86

− 1.34

− 5.06*

 Model 5

0.85

1.00

− 1.80

− 1.26

− 4.99*

Logarithm transformed uACR (n = 1451)

 Model 1

0.09*

1.00

0.22*

0.27*

0.35*

 Model 2

0.11*

1.00

0.23*

0.28*

0.36*

 Model 3

0.11*

1.00

0.23*

0.28*

0.36*

 Model 4

0.09*

1.00

0.22*

0.24*

0.35*

 Model 5

0.09*

1.00

0.23*

0.25*

0.35*

Logarithm transformed Orm (n = 1444)

 Model 1

0.12*

1.00

0.16*

0.15*

0.34*

 Model 2

0.12*

1.00

0.17*

0.16*

0.36*

 Model 3

0.12*

1.00

0.17*

0.16*

0.36*

 Model 4

0.11*

1.00

0.16*

0.13*

0.35*

 Model 5

0.11*

1.00

0.17*

0.13*

0.35*

Logarithm transformed α 1MG (n = 1446)

 Model 1

0.07*

1.00

0.07*

0.08*

0.24*

 Model 2

0.05

1.00

0.05

0.06

0.22*

 Model 3

0.05

1.00

0.05

0.06

0.21*

 Model 4

0.04

1.00

0.05

0.05

0.22*

 Model 5

0.04

1.00

0.05

0.05

0.22*

Logarithm transformed TRF (n = 1445)

 Model 1

0.03

1.00

0.10*

0.15*

0.20*

 Model 2

0.03

1.00

0.11*

0.16*

0.22*

 Model 3

0.03

1.00

0.11*

0.16*

0.22*

 Model 4

0.02

1.00

0.10*

0.13*

0.21*

 Model 5

0.02

1.00

0.10*

0.14*

0.22*

  1. Group 1: moderate-stable group; group 2: low-stable group; group 3: moderate-increasing group; group 4: moderate-decreasing group; group 5: high-stable group
  2. Model 1: no adjustment;
  3. Model 2: adjusted for age, gender;
  4. Model 3: further adjusted for history of myocardial infarction, stroke, cancer;
  5. Model 4: further adjusted for education, physics, smoking status, drinking status, salt habit, triglyceride, total cholesterol, body mass index, LDL, HDL, hsCRP;
  6. Model 5: further adjusted for antihypertensive, hypoglycemic, lipid-lowering drug;
  7. eGFR estimated glomerular filtration rate, α1MG Urinary α1-microglobulin, TRF Transferrinuria, Orm Urinary α1-acid glycoprotein, uACR urinary albumin creatinine ratio