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Table 2 Linear regression analysis between SBP trajectory groups and indicators of kidney disease in 2016

From: Unstably controlled systolic blood pressure trajectories are associated with markers for kidney damage in prediabetic population: results from the INDEED cohort study

 Group 1Group 2Group 3Group 4Group 5
N (%)726 (50.3%)323 (22.3%)176 (12.1%)181 (12.5%)45 (2.8%)
eGFR (n = 1451)
 Model 1− 2.75*1.00− 8.90*− 7.62*− 13.85*
 Model 20.961.00− 1.66− 1.19− 4.81*
 Model 30.991.00− 1.61− 1.13− 4.70*
 Model 40.841.00− 1.86− 1.34− 5.06*
 Model 50.851.00− 1.80− 1.26− 4.99*
Logarithm transformed uACR (n = 1451)
 Model 10.09*1.000.22*0.27*0.35*
 Model 20.11*1.000.23*0.28*0.36*
 Model 30.11*1.000.23*0.28*0.36*
 Model 40.09*1.000.22*0.24*0.35*
 Model 50.09*1.000.23*0.25*0.35*
Logarithm transformed Orm (n = 1444)
 Model 10.12*1.000.16*0.15*0.34*
 Model 20.12*1.000.17*0.16*0.36*
 Model 30.12*1.000.17*0.16*0.36*
 Model 40.11*1.000.16*0.13*0.35*
 Model 50.11*1.000.17*0.13*0.35*
Logarithm transformed α 1MG (n = 1446)
 Model 10.07*1.000.07*0.08*0.24*
 Model 20.051.000.050.060.22*
 Model 30.051.000.050.060.21*
 Model 40.041.000.050.050.22*
 Model 50.041.000.050.050.22*
Logarithm transformed TRF (n = 1445)
 Model 10.031.000.10*0.15*0.20*
 Model 20.031.000.11*0.16*0.22*
 Model 30.031.000.11*0.16*0.22*
 Model 40.021.000.10*0.13*0.21*
 Model 50.021.000.10*0.14*0.22*
  1. Group 1: moderate-stable group; group 2: low-stable group; group 3: moderate-increasing group; group 4: moderate-decreasing group; group 5: high-stable group
  2. Model 1: no adjustment;
  3. Model 2: adjusted for age, gender;
  4. Model 3: further adjusted for history of myocardial infarction, stroke, cancer;
  5. Model 4: further adjusted for education, physics, smoking status, drinking status, salt habit, triglyceride, total cholesterol, body mass index, LDL, HDL, hsCRP;
  6. Model 5: further adjusted for antihypertensive, hypoglycemic, lipid-lowering drug;
  7. eGFR estimated glomerular filtration rate, α1MG Urinary α1-microglobulin, TRF Transferrinuria, Orm Urinary α1-acid glycoprotein, uACR urinary albumin creatinine ratio