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Table 2 The sensitivity of mNGS compared to culture and specificity compared to clinical diagnosis

From: Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection

 

Sensitivity compared to culture

Specificity compared to clinical diagnosis

Without empirical treatment

With empirical treatment

mNGS

90.00% (9/10)

66.67% (6/9)

98.59% (70/71)

Culture

–

–

100.00% (71/71)

Conventional methods

–

–

100.00% (71/71)