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Table 2 The sensitivity of mNGS compared to culture and specificity compared to clinical diagnosis

From: Clinical application and evaluation of metagenomic next-generation sequencing in suspected adult central nervous system infection

 Sensitivity compared to cultureSpecificity compared to clinical diagnosis
Without empirical treatmentWith empirical treatment
mNGS90.00% (9/10)66.67% (6/9)98.59% (70/71)
Culture100.00% (71/71)
Conventional methods100.00% (71/71)