Table 1 Preoperative characteristics of all patients, the glutamate group and the control group (saline)
Variables | All patients (n = 399) | Glutamate (n = 200) | Control (n = 199) | p-value |
|---|---|---|---|---|
Age (years) | 69 [63–75] | 69 [63–76] | 68 [62–75] | 0.45 |
Female gender | 19% (77) | 17% (34) | 22% (43) | 0.26 |
BMI (kg•m2) | 27 [24–30] | 26 [24–76] | 27 [25–30] | 0.18 |
EuroSCORE II | 2.44 [1.66–4.15] | 2.52 [1.72–4.41] | 2.35 [1.61–3.89] | 0.42 |
Diabetes | 23% (93) | 21% (41) | 26% (52) | 0.19 |
Hypertension | 60% (240) | 62% (123) | 59% (117) | 0.54 |
COPD | 7% (27) | 9% (17) | 5% (10) | 0.23 |
NT-proBNP (ng•L−1) | 440 [150–1017] | 470 [185–1070] | 420 [140–999] | 0.31 |
Hemoglobin (g•L−1) | 139 [129–147] | 138 [128–146] | 139 [130–149] | 0.58 |
Troponin T (ng•L−1) | 0 [0–60] | 0 [0–50] | 10[0–70] | 0.46 |
p-Creatinine (μmol•L−1) | 91 [79–104] | 92 [81–106] | 90 [78–104] | 0.24 |
eGFR (mL•min−1•1.73 m−2) | 76 [58–97] | 73 [57–95] | 77 [59–100] | 0.23 |
Cerebrovascular disease | 9% (34) | 8% (16) | 9% (18) | 0.72 |
Three-vessel disease | 77% (306) | 76% (152) | 77% (154) | 0.81 |
Left main stenosis | 36% (145) | 39% (78) | 34% (67) | 0.3 |
AMI < 3 weeks | 65% (260) | 67% (134) | 63% (126) | 0.46 |
History of AMI | 73% (291) | 75% (150) | 71% (141) | 0.37 |
CCS IV | 60% (239) | 59% (119) | 61% (122) | 0.61 |
Angina at rest < 48 h preoperatively | 16% (62) | 14% (27) | 18% (35) | 0.27 |
Moderate LV dysfunction | 13% (52) | 14% (28) | 12% (24) | 0.66 |
Severe LV dysfunction | 4% (16) | 3% (5) | 6% (11) | 0.14 |