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Table 1 Preoperative characteristics of all patients, the glutamate group and the control group (saline)

From: The impact of glutamate infusion on postoperative NT-proBNP in patients undergoing coronary artery bypass surgery: a randomized study

VariablesAll patients
(n = 399)
Glutamate (n = 200)Control
(n = 199)
p-value
Age (years)69 [63–75]69 [63–76]68 [62–75]0.45
Female gender19% (77)17% (34)22% (43)0.26
BMI (kg•m2)27 [24–30]26 [24–76]27 [25–30]0.18
EuroSCORE II2.44 [1.66–4.15]2.52 [1.72–4.41]2.35 [1.61–3.89]0.42
Diabetes23% (93)21% (41)26% (52)0.19
Hypertension60% (240)62% (123)59% (117)0.54
COPD7% (27)9% (17)5% (10)0.23
NT-proBNP (ng•L−1)440 [150–1017]470 [185–1070]420 [140–999]0.31
Hemoglobin (g•L−1)139 [129–147]138 [128–146]139 [130–149]0.58
Troponin T (ng•L−1)0 [0–60]0 [0–50]10[0–70]0.46
p-Creatinine (μmol•L−1)91 [79–104]92 [81–106]90 [78–104]0.24
eGFR (mL•min−1•1.73 m−2)76 [58–97]73 [57–95]77 [59–100]0.23
Cerebrovascular disease9% (34)8% (16)9% (18)0.72
Three-vessel disease77% (306)76% (152)77% (154)0.81
Left main stenosis36% (145)39% (78)34% (67)0.3
AMI < 3 weeks65% (260)67% (134)63% (126)0.46
History of AMI73% (291)75% (150)71% (141)0.37
CCS IV60% (239)59% (119)61% (122)0.61
Angina at rest < 48 h preoperatively16% (62)14% (27)18% (35)0.27
Moderate LV dysfunction13% (52)14% (28)12% (24)0.66
Severe LV dysfunction4% (16)3% (5)6% (11)0.14
  1. Data given as medians [interquartile range] or percentages (number)
  2. AMI < 3 weeks: acute myocardial infarction within 3 weeks of surgery; Angina at rest < 48 h preoperatively: angina at rest within the last 48 h before surgery
  3. BMI body mass index, CCS Canadian Cardiovascular Society, COPD chronic obstructive pulmonary disease, EuroSCORE II European system for cardiac operative risk evaluation II, LV left ventricular, eGFR estimated glomerular filtration rate according to MDRD formula