Fig. 1

Renal expression of Il19, Il20, Il24 and their receptors following unilateral ureteral obstruction (UUO). Renal mRNA expression of Il19 (a), Il20 (b), Il24 (c), Il20ra (d), Il20rb (f) and Il22ra1 (e) of mice underwent UUO and that of controls was determined by real-time RT-PCR in comparison with Gapdh as internal control. The renal protein amount of IL-20RB of WT mice underwent UUO and that of controls was measured by Western blot analysis in comparison with GAPDH as internal control (g and Additional file 1: Figure S4a). Localization of IL-20RB (brown; h) was investigated by immunohistochemical staining in the kidney of mice underwent UUO and in that of controls. Values were expressed as mean ± SD. n = 5–6 in each group; *p < 0.05 vs. control (Kruskal–Wallis test). Scale bar: 50 µm (h)