Fig. 6

Exemplary result of analyzing a T1-weighted MRI data set with the current methods. For patient X, cortical thinning was simulated in frontal regions, for patient Y in more posterior regions. Method 3 was used to analyze the data. The emerging p-map indicates where cortical thinning likely occurs in each patient. Using the method proposed in this text, such maps can be created easily and are therefore simple to implement into clinical practice