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Table 5 Multivariate COX regression analysis of non-fatal stroke

From: Real-world use of ACEI/ARB in diabetic hypertensive patients before the initial diagnosis of obstructive coronary artery disease: patient characteristics and long-term follow-up outcome

 

Univariate

Multivariate

HR (95%CI)

P value

Adjusted HR (95%CI)

P value

Age, y

1.02 (0.99, 1.05)

NS

0.99 (0.97, 1.02)

NS

ACEI/ARB(-)

1.82 (1.13, 2.96)

< 0.05

1.72 (1.05, 2.84)

< 0.05

Beta-blocker before admission

0.54 (0.29, 1.01)

NS

0.56 (0.30, 1.06)

NS

Previous stroke

4.00 (2.52, 6.35)

< 0.001

3.70 (2.29, 5.96)

< 0.001

Hemoglobin, g/L

0.98 (0.96, 0.99)

< 0.05

0.99 (0.97, 1.01)

NS

AMI at admission

2.10 (1.32, 3.35)

< 0.05

1.07 (0.61, 1.86)

NS

LVEF, %

0.95 (0.93, 0.97)

< 0.001

0.96 (0.94, 0.99)

< 0.05

Involved vessel

1.79 (1.28, 2.49)

< 0.05

1.52 (1.08, 2.14)

< 0.05

In-hospital treatment

 ACEI/ARB

0.72 (0.46, 1.14)

NS

0.85 (0.52, 1.38)

NS

 Antiplatelet agents

0.34 (0.16, 0.75)

<0.05

0.49 (0.19, 1.25)

NS

 Statins

0.43 (0.24, 0.76)

<0.05

0.58 (0.30, 1.11)

NS

  1. ACEI/ARB(-) no Angiotensin-converting enzyme inhibitor/Angiotensin receptor blocker therapy before admission, AMI acute myocardial infarction, LVEF left ventricular ejection fraction; NS Non-significant