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Table 1 Baseline demographic clinical characteristic according to SUA trajectories

From: Changing trajectories of serum uric acid and risk of non-alcoholic fatty liver disease: a prospective cohort study

Variables

Total (n=3822)

Trajectory 1 (n=991)

Trajectory 2 (n=1421)

Trajectory 3 (n=1156)

Trajectory 4 (n=254)

P

Age, years

50.49 ± 15.53

44.45 ± 11.76

51.53 ± 15.04

52.95 ± 16.56

56.95 ± 19.04

< 0.001

Male, n (%)

2109 (55.18)

110 (11.10)

727 (51.16)

1024 (88.58)

248 (97.64)

< 0.001

Dietary habits, n (%)

 Meat-based

430 (11.25)

11 3(11.41)

167 (11.75)

116 (10.03)

34 (13.38)

0.348

 Vegetable-based

320 (8.37)

91 (9.18)

124 (8.73)

84 (7.27)

21 (8.27)

 

 Balanced diet

3072 (80.38)

787 (79.41)

1130 (79.52)

956 (82.70)

199 (78.35)

 

Drinking, n (%)

 No

2696 (70.54)

746 (75.28)

979 (68.90)

798 (69.03)

173 (68.11)

0.0171

 Little

754 (19.72)

172 (17.36)

288 (20.27)

239 (20.67)

55 (21.65)

 

 Moderate

301 (7.88)

60 (6.05)

128 (9.01)

90 (7.79)

23 (9.06)

 

 Heavy

71 (1.86)

13 (1.31)

26 (1.83)

29 (2.51)

3 (1.18)

 

 Smoking, n (%)

37 (0.97)

14 (1.41)

13 (0.91)

8 (0.69)

2 (0.79)

0.3779

Exercise, n (%)

 No

499 (13.06)

151 (15.24)

178 (12.53)

147 (12.72)

23 (9.06)

0.1826

 Low

2388 (62.48)

612 (61.76)

904 (63.61)

709 (61.33)

163 (64.17)

 

 Moderate

678 (17.74)

170 (17.15)

244 (17.17)

219 (18.94)

45 (17.71)

 

 High

257 (5.72)

58 (5.85)

95 (6.69)

81 (7.01)

23 (9.06)

 

 BMI, kg/m2

23.19 ± 2.67

22.14 ± 2.66

23.07 ± 2.64

24.01 ± 2.46

24.25 ± 2.26

< 0.001

 Abdominal obesity, n (%)

1016 (26.58)

236 (23.81)

377 (26.53)

324 (28.03)

79 (31.30)

< 0.001

 Dyslipidemia, n (%)

988 (25.85)

220 (22.20)

341 (24.00)

338 (29.24)

89 (35.04)

< 0.001

 MS, n (%)

264 (6.91)

30 (3.03)

78 (5.49)

121 (10.47)

35 (13.78)

< 0.001

 Diabetes, n (%)

120 (3.14)

24 (2.42)

54 (3.80)

35 (3.03)

7 (2.76)

0.274

 Hypertension, n (%)

863 (22.58)

115 (11.60)

304 (21.39)

349 (30.19)

95 (37.40)

< 0.001

 SUA, μmol/L

313.48 ± 80.77

223.27 ± 33.52

296.73 ± 32.67

374.43 ± 38.93

479.72 ± 54.96

< 0.001

 ALT, U/L

17.30 ± 11.49

14.40 ± 7.75

17.24 ± 13.69

19.30 ± 10.85

19.80 ± 10.57

< 0.001

 AST, U/L

19.20 ± 7.32

17.55 ± 4.87

19.36 ± 9.11

20.15 ± 6.64

20.48 ± 5.75

< 0.001

 GGT, U/L

21.23 ± 19.00

15.78 ± 10.19

20.51 ± 17.90

25.16 ± 22.72

28.52 ± 25.31

< 0.001

 BUN, mmol/L

5.20 ± 1.43

4.54 ± 1.19

5.18 ± 1.33

5.58 ± 1.36

6.26 ± 1.85

< 0.001

 SCr, μmol/L

72.94 ± 16.54

60.59 ± 11.30

70.80 ± 13.44

81.24 ± 13.27

95.12 ± 19.59

< 0.001

 eGFR, mL/(min*1.73m2)

98.65 ± 21.32

109.46 ± 21.92

99.19 ± 19.55

92.92 ± 18.19

79.78 ± 19.12

< 0.001

 VAI

1.37 ± 1.00

1.03 ± 0.75

1.19 ± 1.03

1.44 ± 1.45

1.57 ± 1.25

< 0.001

  1. SUA serum uric acid, BMI body mass index, MS metabolic syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT Îł-glutamyl transpeptidase, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, VAI visceral fat index