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Table 1 Baseline demographic clinical characteristic according to SUA trajectories

From: Changing trajectories of serum uric acid and risk of non-alcoholic fatty liver disease: a prospective cohort study

VariablesTotal (n=3822)Trajectory 1 (n=991)Trajectory 2 (n=1421)Trajectory 3 (n=1156)Trajectory 4 (n=254)P
Age, years50.49 ± 15.5344.45 ± 11.7651.53 ± 15.0452.95 ± 16.5656.95 ± 19.04< 0.001
Male, n (%)2109 (55.18)110 (11.10)727 (51.16)1024 (88.58)248 (97.64)< 0.001
Dietary habits, n (%)
 Meat-based430 (11.25)11 3(11.41)167 (11.75)116 (10.03)34 (13.38)0.348
 Vegetable-based320 (8.37)91 (9.18)124 (8.73)84 (7.27)21 (8.27) 
 Balanced diet3072 (80.38)787 (79.41)1130 (79.52)956 (82.70)199 (78.35) 
Drinking, n (%)
 No2696 (70.54)746 (75.28)979 (68.90)798 (69.03)173 (68.11)0.0171
 Little754 (19.72)172 (17.36)288 (20.27)239 (20.67)55 (21.65) 
 Moderate301 (7.88)60 (6.05)128 (9.01)90 (7.79)23 (9.06) 
 Heavy71 (1.86)13 (1.31)26 (1.83)29 (2.51)3 (1.18) 
 Smoking, n (%)37 (0.97)14 (1.41)13 (0.91)8 (0.69)2 (0.79)0.3779
Exercise, n (%)
 No499 (13.06)151 (15.24)178 (12.53)147 (12.72)23 (9.06)0.1826
 Low2388 (62.48)612 (61.76)904 (63.61)709 (61.33)163 (64.17) 
 Moderate678 (17.74)170 (17.15)244 (17.17)219 (18.94)45 (17.71) 
 High257 (5.72)58 (5.85)95 (6.69)81 (7.01)23 (9.06) 
 BMI, kg/m223.19 ± 2.6722.14 ± 2.6623.07 ± 2.6424.01 ± 2.4624.25 ± 2.26< 0.001
 Abdominal obesity, n (%)1016 (26.58)236 (23.81)377 (26.53)324 (28.03)79 (31.30)< 0.001
 Dyslipidemia, n (%)988 (25.85)220 (22.20)341 (24.00)338 (29.24)89 (35.04)< 0.001
 MS, n (%)264 (6.91)30 (3.03)78 (5.49)121 (10.47)35 (13.78)< 0.001
 Diabetes, n (%)120 (3.14)24 (2.42)54 (3.80)35 (3.03)7 (2.76)0.274
 Hypertension, n (%)863 (22.58)115 (11.60)304 (21.39)349 (30.19)95 (37.40)< 0.001
 SUA, μmol/L313.48 ± 80.77223.27 ± 33.52296.73 ± 32.67374.43 ± 38.93479.72 ± 54.96< 0.001
 ALT, U/L17.30 ± 11.4914.40 ± 7.7517.24 ± 13.6919.30 ± 10.8519.80 ± 10.57< 0.001
 AST, U/L19.20 ± 7.3217.55 ± 4.8719.36 ± 9.1120.15 ± 6.6420.48 ± 5.75< 0.001
 GGT, U/L21.23 ± 19.0015.78 ± 10.1920.51 ± 17.9025.16 ± 22.7228.52 ± 25.31< 0.001
 BUN, mmol/L5.20 ± 1.434.54 ± 1.195.18 ± 1.335.58 ± 1.366.26 ± 1.85< 0.001
 SCr, μmol/L72.94 ± 16.5460.59 ± 11.3070.80 ± 13.4481.24 ± 13.2795.12 ± 19.59< 0.001
 eGFR, mL/(min*1.73m2)98.65 ± 21.32109.46 ± 21.9299.19 ± 19.5592.92 ± 18.1979.78 ± 19.12< 0.001
 VAI1.37 ± 1.001.03 ± 0.751.19 ± 1.031.44 ± 1.451.57 ± 1.25< 0.001
  1. SUA serum uric acid, BMI body mass index, MS metabolic syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT γ-glutamyl transpeptidase, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, VAI visceral fat index