|
Variables
|
Total (n=3822)
|
Trajectory 1 (n=991)
|
Trajectory 2 (n=1421)
|
Trajectory 3 (n=1156)
|
Trajectory 4 (n=254)
|
P
|
|---|
|
Age, years
|
50.49 ± 15.53
|
44.45 ± 11.76
|
51.53 ± 15.04
|
52.95 ± 16.56
|
56.95 ± 19.04
|
< 0.001
|
|
Male, n (%)
|
2109 (55.18)
|
110 (11.10)
|
727 (51.16)
|
1024 (88.58)
|
248 (97.64)
|
< 0.001
|
|
Dietary habits, n (%)
|
|
Meat-based
|
430 (11.25)
|
11 3(11.41)
|
167 (11.75)
|
116 (10.03)
|
34 (13.38)
|
0.348
|
|
Vegetable-based
|
320 (8.37)
|
91 (9.18)
|
124 (8.73)
|
84 (7.27)
|
21 (8.27)
| |
|
Balanced diet
|
3072 (80.38)
|
787 (79.41)
|
1130 (79.52)
|
956 (82.70)
|
199 (78.35)
| |
|
Drinking, n (%)
|
|
No
|
2696 (70.54)
|
746 (75.28)
|
979 (68.90)
|
798 (69.03)
|
173 (68.11)
|
0.0171
|
|
Little
|
754 (19.72)
|
172 (17.36)
|
288 (20.27)
|
239 (20.67)
|
55 (21.65)
| |
|
Moderate
|
301 (7.88)
|
60 (6.05)
|
128 (9.01)
|
90 (7.79)
|
23 (9.06)
| |
|
Heavy
|
71 (1.86)
|
13 (1.31)
|
26 (1.83)
|
29 (2.51)
|
3 (1.18)
| |
|
Smoking, n (%)
|
37 (0.97)
|
14 (1.41)
|
13 (0.91)
|
8 (0.69)
|
2 (0.79)
|
0.3779
|
|
Exercise, n (%)
|
|
No
|
499 (13.06)
|
151 (15.24)
|
178 (12.53)
|
147 (12.72)
|
23 (9.06)
|
0.1826
|
|
Low
|
2388 (62.48)
|
612 (61.76)
|
904 (63.61)
|
709 (61.33)
|
163 (64.17)
| |
|
Moderate
|
678 (17.74)
|
170 (17.15)
|
244 (17.17)
|
219 (18.94)
|
45 (17.71)
| |
|
High
|
257 (5.72)
|
58 (5.85)
|
95 (6.69)
|
81 (7.01)
|
23 (9.06)
| |
|
BMI, kg/m2
|
23.19 ± 2.67
|
22.14 ± 2.66
|
23.07 ± 2.64
|
24.01 ± 2.46
|
24.25 ± 2.26
|
< 0.001
|
|
Abdominal obesity, n (%)
|
1016 (26.58)
|
236 (23.81)
|
377 (26.53)
|
324 (28.03)
|
79 (31.30)
|
< 0.001
|
|
Dyslipidemia, n (%)
|
988 (25.85)
|
220 (22.20)
|
341 (24.00)
|
338 (29.24)
|
89 (35.04)
|
< 0.001
|
|
MS, n (%)
|
264 (6.91)
|
30 (3.03)
|
78 (5.49)
|
121 (10.47)
|
35 (13.78)
|
< 0.001
|
|
Diabetes, n (%)
|
120 (3.14)
|
24 (2.42)
|
54 (3.80)
|
35 (3.03)
|
7 (2.76)
|
0.274
|
|
Hypertension, n (%)
|
863 (22.58)
|
115 (11.60)
|
304 (21.39)
|
349 (30.19)
|
95 (37.40)
|
< 0.001
|
|
SUA, μmol/L
|
313.48 ± 80.77
|
223.27 ± 33.52
|
296.73 ± 32.67
|
374.43 ± 38.93
|
479.72 ± 54.96
|
< 0.001
|
|
ALT, U/L
|
17.30 ± 11.49
|
14.40 ± 7.75
|
17.24 ± 13.69
|
19.30 ± 10.85
|
19.80 ± 10.57
|
< 0.001
|
|
AST, U/L
|
19.20 ± 7.32
|
17.55 ± 4.87
|
19.36 ± 9.11
|
20.15 ± 6.64
|
20.48 ± 5.75
|
< 0.001
|
|
GGT, U/L
|
21.23 ± 19.00
|
15.78 ± 10.19
|
20.51 ± 17.90
|
25.16 ± 22.72
|
28.52 ± 25.31
|
< 0.001
|
|
BUN, mmol/L
|
5.20 ± 1.43
|
4.54 ± 1.19
|
5.18 ± 1.33
|
5.58 ± 1.36
|
6.26 ± 1.85
|
< 0.001
|
|
SCr, μmol/L
|
72.94 ± 16.54
|
60.59 ± 11.30
|
70.80 ± 13.44
|
81.24 ± 13.27
|
95.12 ± 19.59
|
< 0.001
|
|
eGFR, mL/(min*1.73m2)
|
98.65 ± 21.32
|
109.46 ± 21.92
|
99.19 ± 19.55
|
92.92 ± 18.19
|
79.78 ± 19.12
|
< 0.001
|
|
VAI
|
1.37 ± 1.00
|
1.03 ± 0.75
|
1.19 ± 1.03
|
1.44 ± 1.45
|
1.57 ± 1.25
|
< 0.001
|
- SUA serum uric acid, BMI body mass index, MS metabolic syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT γ-glutamyl transpeptidase, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, VAI visceral fat index
