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Table 1 Baseline demographic clinical characteristic according to SUA trajectories

From: Changing trajectories of serum uric acid and risk of non-alcoholic fatty liver disease: a prospective cohort study

Variables Total (n=3822) Trajectory 1 (n=991) Trajectory 2 (n=1421) Trajectory 3 (n=1156) Trajectory 4 (n=254) P
Age, years 50.49 ± 15.53 44.45 ± 11.76 51.53 ± 15.04 52.95 ± 16.56 56.95 ± 19.04 < 0.001
Male, n (%) 2109 (55.18) 110 (11.10) 727 (51.16) 1024 (88.58) 248 (97.64) < 0.001
Dietary habits, n (%)
 Meat-based 430 (11.25) 11 3(11.41) 167 (11.75) 116 (10.03) 34 (13.38) 0.348
 Vegetable-based 320 (8.37) 91 (9.18) 124 (8.73) 84 (7.27) 21 (8.27)  
 Balanced diet 3072 (80.38) 787 (79.41) 1130 (79.52) 956 (82.70) 199 (78.35)  
Drinking, n (%)
 No 2696 (70.54) 746 (75.28) 979 (68.90) 798 (69.03) 173 (68.11) 0.0171
 Little 754 (19.72) 172 (17.36) 288 (20.27) 239 (20.67) 55 (21.65)  
 Moderate 301 (7.88) 60 (6.05) 128 (9.01) 90 (7.79) 23 (9.06)  
 Heavy 71 (1.86) 13 (1.31) 26 (1.83) 29 (2.51) 3 (1.18)  
 Smoking, n (%) 37 (0.97) 14 (1.41) 13 (0.91) 8 (0.69) 2 (0.79) 0.3779
Exercise, n (%)
 No 499 (13.06) 151 (15.24) 178 (12.53) 147 (12.72) 23 (9.06) 0.1826
 Low 2388 (62.48) 612 (61.76) 904 (63.61) 709 (61.33) 163 (64.17)  
 Moderate 678 (17.74) 170 (17.15) 244 (17.17) 219 (18.94) 45 (17.71)  
 High 257 (5.72) 58 (5.85) 95 (6.69) 81 (7.01) 23 (9.06)  
 BMI, kg/m2 23.19 ± 2.67 22.14 ± 2.66 23.07 ± 2.64 24.01 ± 2.46 24.25 ± 2.26 < 0.001
 Abdominal obesity, n (%) 1016 (26.58) 236 (23.81) 377 (26.53) 324 (28.03) 79 (31.30) < 0.001
 Dyslipidemia, n (%) 988 (25.85) 220 (22.20) 341 (24.00) 338 (29.24) 89 (35.04) < 0.001
 MS, n (%) 264 (6.91) 30 (3.03) 78 (5.49) 121 (10.47) 35 (13.78) < 0.001
 Diabetes, n (%) 120 (3.14) 24 (2.42) 54 (3.80) 35 (3.03) 7 (2.76) 0.274
 Hypertension, n (%) 863 (22.58) 115 (11.60) 304 (21.39) 349 (30.19) 95 (37.40) < 0.001
 SUA, μmol/L 313.48 ± 80.77 223.27 ± 33.52 296.73 ± 32.67 374.43 ± 38.93 479.72 ± 54.96 < 0.001
 ALT, U/L 17.30 ± 11.49 14.40 ± 7.75 17.24 ± 13.69 19.30 ± 10.85 19.80 ± 10.57 < 0.001
 AST, U/L 19.20 ± 7.32 17.55 ± 4.87 19.36 ± 9.11 20.15 ± 6.64 20.48 ± 5.75 < 0.001
 GGT, U/L 21.23 ± 19.00 15.78 ± 10.19 20.51 ± 17.90 25.16 ± 22.72 28.52 ± 25.31 < 0.001
 BUN, mmol/L 5.20 ± 1.43 4.54 ± 1.19 5.18 ± 1.33 5.58 ± 1.36 6.26 ± 1.85 < 0.001
 SCr, μmol/L 72.94 ± 16.54 60.59 ± 11.30 70.80 ± 13.44 81.24 ± 13.27 95.12 ± 19.59 < 0.001
 eGFR, mL/(min*1.73m2) 98.65 ± 21.32 109.46 ± 21.92 99.19 ± 19.55 92.92 ± 18.19 79.78 ± 19.12 < 0.001
 VAI 1.37 ± 1.00 1.03 ± 0.75 1.19 ± 1.03 1.44 ± 1.45 1.57 ± 1.25 < 0.001
  1. SUA serum uric acid, BMI body mass index, MS metabolic syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT γ-glutamyl transpeptidase, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, VAI visceral fat index