| Variables | Total (n=3822) | Trajectory 1 (n=991) | Trajectory 2 (n=1421) | Trajectory 3 (n=1156) | Trajectory 4 (n=254) | P |
|---|
| Age, years | 50.49 ± 15.53 | 44.45 ± 11.76 | 51.53 ± 15.04 | 52.95 ± 16.56 | 56.95 ± 19.04 | < 0.001 |
| Male, n (%) | 2109 (55.18) | 110 (11.10) | 727 (51.16) | 1024 (88.58) | 248 (97.64) | < 0.001 |
| Dietary habits, n (%) |
| Meat-based | 430 (11.25) | 11 3(11.41) | 167 (11.75) | 116 (10.03) | 34 (13.38) | 0.348 |
| Vegetable-based | 320 (8.37) | 91 (9.18) | 124 (8.73) | 84 (7.27) | 21 (8.27) | |
| Balanced diet | 3072 (80.38) | 787 (79.41) | 1130 (79.52) | 956 (82.70) | 199 (78.35) | |
| Drinking, n (%) |
| No | 2696 (70.54) | 746 (75.28) | 979 (68.90) | 798 (69.03) | 173 (68.11) | 0.0171 |
| Little | 754 (19.72) | 172 (17.36) | 288 (20.27) | 239 (20.67) | 55 (21.65) | |
| Moderate | 301 (7.88) | 60 (6.05) | 128 (9.01) | 90 (7.79) | 23 (9.06) | |
| Heavy | 71 (1.86) | 13 (1.31) | 26 (1.83) | 29 (2.51) | 3 (1.18) | |
| Smoking, n (%) | 37 (0.97) | 14 (1.41) | 13 (0.91) | 8 (0.69) | 2 (0.79) | 0.3779 |
| Exercise, n (%) |
| No | 499 (13.06) | 151 (15.24) | 178 (12.53) | 147 (12.72) | 23 (9.06) | 0.1826 |
| Low | 2388 (62.48) | 612 (61.76) | 904 (63.61) | 709 (61.33) | 163 (64.17) | |
| Moderate | 678 (17.74) | 170 (17.15) | 244 (17.17) | 219 (18.94) | 45 (17.71) | |
| High | 257 (5.72) | 58 (5.85) | 95 (6.69) | 81 (7.01) | 23 (9.06) | |
| BMI, kg/m2 | 23.19 ± 2.67 | 22.14 ± 2.66 | 23.07 ± 2.64 | 24.01 ± 2.46 | 24.25 ± 2.26 | < 0.001 |
| Abdominal obesity, n (%) | 1016 (26.58) | 236 (23.81) | 377 (26.53) | 324 (28.03) | 79 (31.30) | < 0.001 |
| Dyslipidemia, n (%) | 988 (25.85) | 220 (22.20) | 341 (24.00) | 338 (29.24) | 89 (35.04) | < 0.001 |
| MS, n (%) | 264 (6.91) | 30 (3.03) | 78 (5.49) | 121 (10.47) | 35 (13.78) | < 0.001 |
| Diabetes, n (%) | 120 (3.14) | 24 (2.42) | 54 (3.80) | 35 (3.03) | 7 (2.76) | 0.274 |
| Hypertension, n (%) | 863 (22.58) | 115 (11.60) | 304 (21.39) | 349 (30.19) | 95 (37.40) | < 0.001 |
| SUA, μmol/L | 313.48 ± 80.77 | 223.27 ± 33.52 | 296.73 ± 32.67 | 374.43 ± 38.93 | 479.72 ± 54.96 | < 0.001 |
| ALT, U/L | 17.30 ± 11.49 | 14.40 ± 7.75 | 17.24 ± 13.69 | 19.30 ± 10.85 | 19.80 ± 10.57 | < 0.001 |
| AST, U/L | 19.20 ± 7.32 | 17.55 ± 4.87 | 19.36 ± 9.11 | 20.15 ± 6.64 | 20.48 ± 5.75 | < 0.001 |
| GGT, U/L | 21.23 ± 19.00 | 15.78 ± 10.19 | 20.51 ± 17.90 | 25.16 ± 22.72 | 28.52 ± 25.31 | < 0.001 |
| BUN, mmol/L | 5.20 ± 1.43 | 4.54 ± 1.19 | 5.18 ± 1.33 | 5.58 ± 1.36 | 6.26 ± 1.85 | < 0.001 |
| SCr, μmol/L | 72.94 ± 16.54 | 60.59 ± 11.30 | 70.80 ± 13.44 | 81.24 ± 13.27 | 95.12 ± 19.59 | < 0.001 |
| eGFR, mL/(min*1.73m2) | 98.65 ± 21.32 | 109.46 ± 21.92 | 99.19 ± 19.55 | 92.92 ± 18.19 | 79.78 ± 19.12 | < 0.001 |
| VAI | 1.37 ± 1.00 | 1.03 ± 0.75 | 1.19 ± 1.03 | 1.44 ± 1.45 | 1.57 ± 1.25 | < 0.001 |
- SUA serum uric acid, BMI body mass index, MS metabolic syndrome, ALT alanine aminotransferase, AST aspartate aminotransferase, GGT γ-glutamyl transpeptidase, BUN blood urea nitrogen, SCr serum creatinine, eGFR estimated glomerular filtration rate, VAI visceral fat index
