The MK2 pathway is linked to G-CSF, cytokine production and metastasis in gastric cancer: a novel intercorrelation analysis approach

Table 2 Linear association between cytokines and MK2 in 30 subjects (15 with metastasis and 15 without metastasis)

	Analytes*	\(\hat{\beta }\)	T-stat	p-value**	r	R²
1	IL1B	1.00825	6.31	0.00002	0.77188	0.5958
2	GMCSF	0.38789	6.05	0.00005	0.75842	0.5752
3	TNFa	0.96889	5.90	0.00007	0.75020	0.5628
4	IL6	0.00182	5.64	0.00013	0.73519	0.5405
5	Mip1B	0.44855	5.09	0.00052	0.70000	0.4900
6	IFNa2	0.13301	3.77	0.01683	0.58737	0.3450
7	MCP1	0.00170	3.61	0.02400	0.57105	0.3261
8	GCSF	0.00315	3.45	0.03440	0.55353	0.3064
9	IL2	0.90769	3.29	0.04878	0.53526	0.2865
10	VEGF	0.03220	3.22	0.05451	0.52726	0.2780
11	Mip1a	0.03774	3.18	0.05710	0.52211	0.2726
12	IL8	0.00086329	3.09	0.06611	0.51166	0.2618
13	EGF	0.33859	3.01	0.07600	0.50100	0.2510
14	TNFB	0.31614	2.76	0.12569	0.46893	0.2199
15	IL4	0.13164	2.64	0.15080	0.45332	0.2055
16	IL10	0.03301	2.56	0.16652	0.44181	0.1952
17	IL7	0.22821	2.35	0.23334	0.41231	0.1700
18	IFNg	0.28550	2.29	0.24001	0.40336	0.1627
19	IL5	1.07906	2.00	0.36824	0.35903	0.1289
20	IL_12p40	0.15047	1.93	0.37360	0.34756	0.1208
21	IL13	0.47673	1.69	0.44061	0.30984	0.0960
22	IL15	0.40696	1.56	0.44061	0.28792	0.0829
23	IL17A	0.32704	1.75	0.44061	0.31843	0.1014
24	IL_12p70	0.21885	1.51	0.44061	0.27875	0.0777
25	IL1a	− 0.03150	− 0.40	0.90517	0.07681	0.0059
26	IP10	− 0.00101	− 0.06	0.95183	0.01000	0.0001

Italic values indicate significance of p < 0.05
*Nine significant associations between cytokines and MK2 were identified (total cytokines 26)
**Sidak correction for p-values is used

ISSN: 1479-5876