Journal of Translational Medicine

Table 2 Association between clinical variables and serum HER2 levels

From: Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study

	Entire study population			CAD group			Control group
	β coefficient	95% CI	P	β coefficient	95% CI	P	β coefficient	95% CI	P
Age	− 0.158	− 0.272 to − 0.044	0.007	− 0.112	− 0.298 to 0.075	0.240	− 0.257	− 0.395 to − 0.119	< 0.001
Male gender	0.048	− 0.171 to 0.268	0.665	− 0.202	− 0.559 to 0.155	0.265	0.205	− 0.059 to 0.470	0.127
BMI	0.212	0.114 to 0.310	< 0.001	0.335	0.183 to 0.487	< 0.001	0.133	0.008 to 0.257	0.037
Current smoking	0.164	− 0.059 to 0.387	0.149	0.287	− 0.032 to 0.606	0.078	− 0.088	− 0.392 to 0.215	0.567
Hypertension	− 0.174	− 0.360 to 0.012	0.067	− 0.297	− 0.588 to − 0.007	0.045	− 0.096	− 0.324 to 0.132	0.408
HbA1c	0.086	− 0.005 to 0.176	0.064	0.032	− 0.090 to 0.154	0.607	0.093	− 0.053 to 0.238	0.210
LDL-C	0.180	0.090 to 0.269	< 0.001	0.106	− 0.022 to 0.234	0.106	0.218	0.085 to 0.351	0.001
HDL-C	0.082	− 0.010 to 0.175	0.080	0.013	− 0.106 to 0.132	0.835	0.172	− 0.007 to 0.351	0.060
Triglycerides	0.184	0.092 to 0.276	< 0.001	0.175	0.049 to 0.301	0.007	0.197	0.053 to 0.341	0.008
eGFR	− 0.021	− 0.126 to 0.085	0.697	0.067	− 0.081 to 0.216	0.372	− 0.084	− 0.235 to 0.067	0.271

Multivariate linear regression analysis with HER2 levels as a dependent variable in the entire study population, CAD group, and control group, respectively. The β coefficient for the continuous variables is expressed as per 1-SD increase to allow comparison among effects
BMI body mass index, CI confidence interval, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol

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