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Table 2 Association between clinical variables and serum HER2 levels

From: Association between serum HER2/ErbB2 levels and coronary artery disease: a case–control study

  Entire study population CAD group Control group
β coefficient 95% CI P β coefficient 95% CI P β coefficient 95% CI P
Age − 0.158 − 0.272 to − 0.044 0.007 − 0.112 − 0.298 to 0.075 0.240 − 0.257 − 0.395 to − 0.119 < 0.001
Male gender 0.048 − 0.171 to 0.268 0.665 − 0.202 − 0.559 to 0.155 0.265 0.205 − 0.059 to 0.470 0.127
BMI 0.212 0.114 to 0.310 < 0.001 0.335 0.183 to 0.487 < 0.001 0.133 0.008 to 0.257 0.037
Current smoking 0.164 − 0.059 to 0.387 0.149 0.287 − 0.032 to 0.606 0.078 − 0.088 − 0.392 to 0.215 0.567
Hypertension − 0.174 − 0.360 to 0.012 0.067 − 0.297 − 0.588 to − 0.007 0.045 − 0.096 − 0.324 to 0.132 0.408
HbA1c 0.086 − 0.005 to 0.176 0.064 0.032 − 0.090 to 0.154 0.607 0.093 − 0.053 to 0.238 0.210
LDL-C 0.180 0.090 to 0.269 < 0.001 0.106 − 0.022 to 0.234 0.106 0.218 0.085 to 0.351 0.001
HDL-C 0.082 − 0.010 to 0.175 0.080 0.013 − 0.106 to 0.132 0.835 0.172 − 0.007 to 0.351 0.060
Triglycerides 0.184 0.092 to 0.276 < 0.001 0.175 0.049 to 0.301 0.007 0.197 0.053 to 0.341 0.008
eGFR − 0.021 − 0.126 to 0.085 0.697 0.067 − 0.081 to 0.216 0.372 − 0.084 − 0.235 to 0.067 0.271
  1. Multivariate linear regression analysis with HER2 levels as a dependent variable in the entire study population, CAD group, and control group, respectively. The β coefficient for the continuous variables is expressed as per 1-SD increase to allow comparison among effects
  2. BMI body mass index, CI confidence interval, eGFR estimated glomerular filtration rate, HbA1c hemoglobin A1c, HDL-C high-density lipoprotein cholesterol, LDL-C low-density lipoprotein cholesterol