Table 1 Differences of phenotypes, locations, proportion of B cells, and subset ratios between mouse and human transitional B cells

Phenotypes

T1: CD24^hiCD21^loCD23^loIgM^hiIgD^lo

T2: CD24^hiCD21^hiCD23^hiIgM^hiIgD^hi

T1: CD19⁺CD24^hiCD21^loCD23^loIgM^hiIgD^lo

T2: CD19⁺CD24^hiCD21^hiCD23^hiIgM^hiIgD^hi

T1: CD24⁺⁺⁺CD21⁻CD23⁻IgM⁺⁺⁺IgD⁻CD93⁺CD62L⁻

T2: CD24⁺⁺⁺CD21⁺⁺CD23⁺⁺IgM⁺⁺⁺IgD⁺⁺CD93⁺CD62L⁻

T3: D24⁺⁺⁺CD21⁺⁺CD23⁺⁺IgM⁺⁺IgD⁺⁺CD93⁺CD62L⁺

T1: R123⁺CD38⁺⁺⁺CD24⁺⁺⁺CD10⁺IgD⁺CD27⁻

T2: R123⁺CD38⁺⁺CD24⁺⁺CD10⁺IgD⁺CD27⁻

T3: R123⁺CD38⁺CD24⁺CD10⁺IgD⁺CD27⁻

T1: CD19⁺CD24^hiCD38^hiCD27IgM^hiIgD^loCD10^hiCD21^loCD32^hi

T2: CD19⁺CD24^hiCD38^hiCD27IgMⁱⁿIgDⁱⁿCD10ⁱⁿCD21^loCD32ⁱⁿ

T3: CD19⁺CD24^hiCD38^hiCD27IgM^loIgD^loCD10^loCD21^loCD32^lo

CD27⁺TrB: CD19⁺CD24^hiCD38^hiCD27⁺

Locations

BM, PB, Spleen

BM, PB, CB and secondary lymphoid tissues (spleen, tonsil, lymph node and GALT)

The proportion of B cells

BM: 15–20%

BM: 6.3%

PB: 15–20%

PB: 4%

Spleen: 10–15%

CB: 50%

Subset ratios (TrB: FM B)

BM 1:0.6

BM 1:2.1

PB 1:0.4

PB 1:2.2

Spleen 1:3.7

Spleen 1:21.9