Fig. 1

PD-induced mitophagy in SI-AKI model mice. The mice were subjected to CLP, administered PD (30 mg/kg) or vehicle, and sacrificed at 12 h after CLP. a Western blot analysis of the following proteins was performed: TOM20 and TIM23 (mitochondrial markers), PGC-1α and mtTFA (mitochondrial biogenesis markers), and LC3II/I, P62 and phosphorylated P62 (autophagy-associated proteins). Quantification of b TOM20, c TIM23, d LC3II/I, e P62, f P62 phosphorylation, g PGC-1α, and h mt-TFA