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Fig. 6 | Journal of Translational Medicine

Fig. 6

From: An engineering probiotic producing defensin-5 ameliorating dextran sodium sulfate-induced mice colitis via Inhibiting NF-kB pathway

Fig. 6

Protective effect of NZ9000SHD-5 on intestinal tight junctions in vitro. a Changes in TEER in Caco-2 cell monolayers exposed to different treatment was determined at 1, 2, 4, 8, 12 and 24 h. b FITC-dextrum quantification was compared between groups. Relative changes of gene expression of c zo-1 and d occludin were measured by real-time PCR. e Expression of TJ-related proteins in Caco-2 cells. f Cytoskeleton integrity, with zo-1 shown in green and occludin in red. Differences between groups were determined by ANOVA followed by the post hoc LSD test (n = 6). *p < 0.05 as compared to the DSS group. #p < 0.05 as compared to the NZ9000 group

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Journal of Translational Medicine

ISSN: 1479-5876

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