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Table 1 Characteristics of the included trials and participants

From: Use of thiazide diuretics for the prevention of recurrent kidney calculi: a systematic review and meta-analysis

Author

Year

Patients

Gender (M/F)

Mean age (year)

Sample

Events/total (intervention)

Events/total (placebo)

Drugs (intervention)

Drugs (control)

Lost visits

Percent of lost visits

Follow-up (month)

Borghi et al. [20]

1993

Recurrent calcium stones

I: 18/7

C: 20/5

I: 46.5

C: 42.8

40

3/19

9/21

Indapamide

No treatment

10

20%

36

Brocks et al. [10]

1981

Recurrent calcium stones

NR

16–49

62

5/33

5/29

Bendroflumethiazide

Placebo

0

0

48

Ettinger et al. [19]

1988

Recurrent calcium stones

NR

T: L 49.8, H 49.3

C: 48.9

73

6/42

14/31

Chlorthalidone

Placebo

NR

NR

36

Fernández-Rodríguez et al. [18]

2006

Recurrent calcium stones

NR

NR

100

16/50

28/50

Hydrochlorothiazide

No treatment

0

0

36

Laerum et al. [17]

1984

Recurrent calcium stones

38/12

T: 45.8

C: 42.7

48

5/23

12/25

Hydrochlorothiazide + KCl

Placebo

2

4%

12–51

Mortensen et al. [16]

1986

Recurrent kidney stones

All male

20–49

22

0/12

4/10

Bendroflumethiazide + KCl

Placebo

5

18.5%

72

Ohkawa et al. [15]

1992

Calcium stones with hypercalciuria

I: 45/37

C: 52/41

I: 48.7

C: 46.9

175

11/82

41/93

Trichlormethiazide

No treatment

35

16.7%

6–68

Scholz et al. [9]

1982

Recurrent calcium calculi

I: 14/11

C: 17/9

I: 46

C: 41

51

6/25

6/26

Hydrochlorothiazide

Placebo

3

5.6%

12

  1. I intervention group, C control group, NR not reported, L low dose group, H high dose group, KCl potassium chloride