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Table 1 Characteristics of the included trials and participants

From: Use of thiazide diuretics for the prevention of recurrent kidney calculi: a systematic review and meta-analysis

AuthorYearPatientsGender (M/F)Mean age (year)SampleEvents/total (intervention)Events/total (placebo)Drugs (intervention)Drugs (control)Lost visitsPercent of lost visitsFollow-up (month)
Borghi et al. [20]1993Recurrent calcium stonesI: 18/7
C: 20/5
I: 46.5
C: 42.8
403/199/21IndapamideNo treatment1020%36
Brocks et al. [10]1981Recurrent calcium stonesNR16–49625/335/29BendroflumethiazidePlacebo0048
Ettinger et al. [19]1988Recurrent calcium stonesNRT: L 49.8, H 49.3
C: 48.9
736/4214/31ChlorthalidonePlaceboNRNR36
Fernández-Rodríguez et al. [18]2006Recurrent calcium stonesNRNR10016/5028/50HydrochlorothiazideNo treatment0036
Laerum et al. [17]1984Recurrent calcium stones38/12T: 45.8
C: 42.7
485/2312/25Hydrochlorothiazide + KClPlacebo24%12–51
Mortensen et al. [16]1986Recurrent kidney stonesAll male20–49220/124/10Bendroflumethiazide + KClPlacebo518.5%72
Ohkawa et al. [15]1992Calcium stones with hypercalciuriaI: 45/37
C: 52/41
I: 48.7
C: 46.9
17511/8241/93TrichlormethiazideNo treatment3516.7%6–68
Scholz et al. [9]1982Recurrent calcium calculiI: 14/11
C: 17/9
I: 46
C: 41
516/256/26HydrochlorothiazidePlacebo35.6%12
  1. I intervention group, C control group, NR not reported, L low dose group, H high dose group, KCl potassium chloride