Fig. 2

sCLU overexpression contributed to the malignant behaviors of HCC cells. a sCLU expression in HepG2 cells transfected with NC or OE-sCLU was detected by western blotting. b sCLU overexpression was detected by RT-qPCR. c The migration of HepG2 cells transfected with NC or OE-sCLU was detected by wound-healing assay. d The relative migration distance in C. e The invasion of HepG2 cells was detected by transwell assay. f The relative invasive cell number in e. g, h MTT assay was used to detect the viability of HepG2 cells after sorafenib or doxorubicin treatment. i The xenograft tumors derived from HepG2 cells transfected with OE-sCLU or NC plasmids. j The tumor growth curves of each group identified on the surface of mice. k The final volume of each group was calculated. Scale bar, 100 µm. **P < 0.01