Fig. 1
From: Suppression of p66Shc prevents hyperandrogenism-induced ovarian oxidative stress and fibrosis
Ovarian morphology is improved after treatment with resveratrol in dehydroepiandrosterone-exposed rats. Rats received DHEA for induction of polycystic ovarian syndrome together with or without resveratrol treatment. a Rat body weights were measured on the day of sacrifice (day 36). b Average weight of both ovaries was measured. c Photographs of the morphology of the ovaries from each treatment group were shown. d Ovarian and follicular morphology was assessed by H&E staining (5×). The percentage of each follicle was shown on the right. n = 7 in each group. Three independent experiments were performed with similar results. Data are shown as the mean ± SD. ##p ≤ 0.01, ###p ≤ 0.001 vs. Blank; *p ≤ 0.05, **p ≤ 0.01, ***p ≤ 0.001 vs. DHEA treatment. DHEA, dehydroepiandrosterone; Res, resveratrol; PAF, preantral and early antral follicle; AF, antral follicle; CF, cystic follicles; CL, corpus luteum