Fig. 2

CD38⁺ Tcm is associated with lower activation and higher CD127 expression levels. a FACS analysis of CD25 and CD69 expression on CD4⁺CD38⁺ Tcm, CD4⁺HLA-DR-Tcm and CD4⁺HLA-DR⁺ T cells in PBMCs obtained from HIV-infected individuals receiving ART for > 5 years. Quantification of the percentages of CD25⁺ cells (b) and CD69⁺ (c) cells in CD4⁺CD38⁺ Tcm, CD4⁺HLA-DR⁻ Tcm, and CD4⁺HLA-DR⁺ T cell compartments. Paired t-test; data from 3 donors. d FACS analysis of CD127 expression on CD4⁺CD38⁺ Tcm, CD4⁺HLA-DR⁻ Tcm, and CD4⁺HLA-DR⁺ T cells with PBMCs obtained from HIV-infected individuals receiving ART for > 5 years. e Quantification of the percentages of CD127⁺ cells within the CD4⁺CD38⁺ Tcm, CD4⁺HLA-DR⁻ Tcm, and CD4⁺HLA-DR⁺ T cell populations. Paired t-test; n = 3 donors