Variables | Univariable analysis | Multivariable analysis | ||
---|---|---|---|---|
HR (95% CI) | p value | HR (95% CI) | p value | |
Training cohort | ||||
 Age (≤ 59 vs > 59) | 0.96 (0.65–1.48) | 0.906 |  |  |
 Gender (Male vs female) | 0.78 (0.46–1.32) | 0.357 |  |  |
 Tobacco use (Y vs N) | 1.30 (0.82–2.05) | 0.265 |  |  |
 Alcohol use (Y vs N) | 1.10 (0.73–1.67) | 0.657 |  |  |
 Tumor location (U vs M vs L) | 1.26 (0.86–1.85) | 0.238 |  |  |
 Differentiation (H vs Mt vs L) | 2.49 (1.63–3.81) | < 0.001 | 2.23 (1.45–3.44) | < 0.001 |
 TNM stage (III vs I, II) | 2.41 (1.57–3.70) | < 0.001 | 1.93 (1.24–3.01) | 0.003 |
 LncRNA signature (H-risk vs L- risk) | 2.36 (1.41–3.95) | < 0.001 | 2.28 (1.36–3.82) | 0.002 |
Independent cohort | ||||
 Age (≤ 59 vs > 59) | 1.04 (0.64–1.70) | 0.868 |  |  |
 Gender (Male vs female) | 1.14 (0.67–1.95) | 0.632 |  |  |
 Tobacco use (Y vs N) | 1.03 (0.62–1.73) | 0.901 |  |  |
 Alcohol use (Y vs N) | 1.05 (0.63–1.73) | 0.858 |  |  |
 Tumor location (U vs M vs L) | 0.98 (0.64–1.51) | 0.941 |  |  |
 Differentiation (H vs Mt vs Low) | 1.33 (0.94–1.89) | 0.104 |  |  |
 TNM stage (III vs I, II) | 2.66 (1.60–4.40) | < 0.001 | 2.58 (1.55–4.27) | < 0.001 |
 LncRNA signature (H-risk vs L-risk) | 2.36 (1.41–3.95) | 0.001 | 2.28 (1.36–3.82) | 0.002 |