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Table 1 The correlation of SELENBP1 expression with clinicopathological features in TCGA-BLCA cohort (n = 406)

From: Selenium-binding protein 1 transcriptionally activates p21 expression via p53-independent mechanism and its frequent reduction associates with poor prognosis in bladder cancer

VariablesSELENBP1 expressionp-value
High (n = 160)Low (n = 246)
Age (years)   
 < 7086 (40%)128 (60%)0.761
 ≥ 7074 (39%)118 (61%) 
Sex   
 Female44 (42%)62 (58%)0.644
 Male116 (39%)184 (61%) 
Histologic subtype   
 Papillary63 (48%)69 (52%)0.023a
 Non-papillary96 (36%)173 (64%) 
 Missing1 (20%)4 (80%) 
Histologic grade   
 Low grade9 (43%)12 (57%)0.819
 High grade149 (39%)233 (61%) 
 Missing2 (67%)1 (33%) 
Primary tumor   
 T1/T256 (46%)66 (54%)0.090b
 T3/T491 (36%)160 (64%) 
 Missing13 (39%)20 (61%) 
Regional lymph node   
 Negative93 (40%)142 (60%)0.430c
 Positive45 (35%)84 (65%) 
 Missing22 (52%)20 (48%) 
Distant metastasis   
 M076 (39%)120 (61%)0.057d
 M11 (9%)10 (91%) 
 Missing83 (42%)116 (58%) 
Lymphovascular invasion (LVI)   
 Negative59 (46%)70 (54%)0.469e
 Positive62 (41%)89 (59%) 
 Missing39 (31%)87 (69%) 
TNM stage   
 I/II62 (47%)69 (53%)0.029f
 III/IV97 (36%)176 (64%) 
 Missing1 (50%)1 (50%) 
  1. TCGA-BLCA The Cancer Genome Atlas bladder cancer cohort
  2. Based on Pearson χ2 test, p-value is calculated using Fisher’s exact test; Italics values denote p-value < 0.05
  3. aPapillary vs. non-papillary
  4. bT1/T2 vs. T3/T4
  5. cNegative vs. positive
  6. dM0 vs. M1
  7. eNegative vs. positive
  8. fI/II vs. III/IV