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Table 2 irAEs occurrence according to the system/organ involved

From: Immunotherapy Bridge 2019 and Melanoma Bridge 2019: meeting abstracts

Any grade irAEs

Early-irAEs (patients-%)

Late-irAEs (patients-%)

P value

Overall population

175 (55.0)

110 (34.6)

0.0013

 Skin

68 (38.9)

45 (40.9)

0.8212

 Endocrine

49 (28.0)

17 (15.4)

0.0508

 Gastrointestinal

39 (22.3)

15 (13.6)

0.1314

 Pneumological

12 (6.9)

7 (6.4)

0.8792

 Haepatic

8 (4.6)

3 (2.7)

0.5411

 Rheumatologic

37 (21.1)

26 (23.6)

0.6943

 Neurologic

1 (0.6)

7 (6.4)

0.0076

 Others

47 (26.9)

11 (10.0)

0.0044

G3/G4 irAEs

13 (4.1)

12 (3.8)

0.8446