| |
Women (n = 140)
|
Men (n = 147)
|
|---|
|
GG (n = 90)
|
AG (n = 28)
|
AA (n = 22)
|
P*
|
GG (n = 109)
|
AG (n = 30)
|
AA (n = 8)
|
P*
|
|---|
|
LDL-C (mg/dL)
|
116.66 (34.00)
|
124.32 (37.89)
|
122.82 (28.47)
|
0.645
|
122.07 (29.43)
|
114.48 (24.87)
|
125.68 (27.63)
|
0.563
|
|
HDL (mg/dL)
|
46.40 (9.37)
|
50.05 (7.87)
|
47.50 (10.25)
|
0.347
|
43.00 (6.89)
|
39.22 (6.87)
|
43.00 (6.74)
|
0.122
|
|
Cholesterol (mg/dL)
|
185.71 (36.83)
|
191.83 (36.94)
|
190.50 (33.59)
|
0.786
|
191.16 (32.40)
|
180.05 (27.49)
|
199.80 (32.87)
|
0.316
|
|
TG (mg/dL)
|
113.26 (43.56)
|
87.27 (34.73)
|
100.85 (34.30)
|
0.06
|
130.49 (70.65)
|
131.72 (62.35)
|
155.60 (53.83)
|
0.732
|
|
Glucose (mg/dL)
|
91.08 (10.34)
|
88.38 (12.08)
|
95.00 (11.02)
|
0.235
|
93.95 (12.82)
|
96.94 (25.40)
|
113.80 (39.96)
|
0.05
|
|
Insulin (U/mL)
|
18.36 (9.25)
|
11.81 (6.77)
|
15.73 (10.43)
|
0.329
|
14.16 (7.63)
|
13.81 (6.76)
|
21.16 (11.06)
|
0.139
|
|
HOMA-IR
|
4.22 (2.18)
|
2.66 (1.66)
|
3.68 (2.57)
|
0.531
|
3.22 (1.77)
|
3.38 (1.99)
|
5.50 (2.52)
|
0.035
|
|
QUICKI
|
0.31 (0.02)
|
0.34 (0.03)
|
0.32 (0.03)
|
0.116
|
0.32 (0.02)
|
0.32 (0.02)
|
0.30 (0.02)
|
0.143
|
|
α-MSH (ng/L)
|
168.14 (97.74)
|
274.41 (213.43)
|
271.55 (231.49)
|
0.010
|
226.61 (172.86)
|
201.94 (122.25)
|
299.61 (249.29)
|
0.533
|
|
AgRP (pg/mL)
|
24.12 (9.52)
|
33.94 (21.69)
|
34.86 (27.11)
|
0.019
|
33.93 (19.92)
|
31.5 (13.04)
|
38.80 (29.97)
|
0.789
|
- Italic values indicate significance of P value (P < 0.05)
- TC total cholesterol, TG triglyceride, HDL-C high density lipoprotein cholesterol, LDL-C low density lipoprotein cholesterol, HOMA-IR homeostatic model assessment for insulin resistance, QUICKI quantitative insulin sensitivity check index, α-MSH alpha-melanocyte-stimulating hormone, AgRP, agouti-related peptide; all variables data are presented based on mean (SD)
- *P values based on ANCOVA after adjustment for age
