Skip to main content

Table 5 miR expressions in diagnostic ALL samples compared to controls (PB PFP samples, advanced qPCR results)

From: Circulating microRNAs as minimal residual disease biomarkers in childhood acute lymphoblastic leukemia

Subgroups

miR-128-3p log2FC (adj. p value)

miR-181a-5p log2FC (adj. p value)

miR-181b-5p log2FC (adj. p value)

miR-222-3p log2FC (adj. p value)

Karyotype: hyperdiploid

3.39 (7.05*10−4)

NS

NS

2.09 (4.06*10−2)

Karyotype: t(12;21)

5.93 (9.59*10−10)

2.56 (1.38*10−2)

3.84 (2.26*10−4)

3.34 (2.21*10−4)

Karyotype: normala

4.23 (1.78*10−5)

3.45 (5.35*10−4)

4.31 (4.73*10−5)

2.63 (4.76*10−3)

Whole cohort

4.52 (3.48*10−9)

2.46 (2.11*10−3)

3.46 (4.73*10−5)

2.68 (2.15*10−4)

  1. Values in the table indicate the average log2 fold change between cases and controls
  2. NS no significant correlation
  3. aNormal karyotype: no alteration on FISH, DNA index diploid and cytogenetics normal or unsuccessful