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Table 1 Clinicopathological characteristics baseline in relation to AQP9 expression level in FUSCC cohort

From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma

Characteristics

FUSCC cohort

(N = 380)

AQP9 expression

χ2

p

High

(N = 190)

Low

(N = 190)

N (%)

     

Age

   

0.296

0.587

 < 60 years

253 (66.6)

124 (65.3)

129 (67.9)

  

 ≥ 60 years

127 (33.4)

66 (34.7)

61 (32.1)

  

Gender

   

0.435

0.510

 Male

258 (67.9)

132 (69.5)

126 (66.3)

  

 Female

122 (32.1)

58 (30.5)

64 (33.7)

  

BMI

   

0.541

0.462

 < 25 kg/m2

231 (60.8)

112 (58.9)

119 (62.6)

  

 ≥ 25 kg/m2

149 (39.2)

78 (41.1)

71 (37.4)

  

pT stage

   

34.336

< 0.001

 T1–T2

307 (80.8)

131 (68.9)

176 (92.6)

  

 T3–T4

73 (19.2)

59 (31.1)

14 (7.4)

  

pN stage

   

14.246

< 0.001

 N0

334 (87.9)

155 (81.6)

179 (94.2)

  

 N1

46 (12.1)

35 (18.4)

11 (5.8)

  

pM stage

   

40.347

< 0.001

 M0

310 (81.6)

131 (68.9)

179 (94.2)

  

 M1

70 (18.4)

59 (31.1)

11 (5.8)

  

AJCC stagea

   

34.072

< 0.001

 I–II

292 (76.8)

122 (64.2)

170 (89.5)

  

 III–IV

88 (23.2)

68 (35.8)

20 (10.5)

  

ISUP grade

   

4.218

0.040

 G1–G2

182 (47.9)

81 (42.6)

101 (53.2)

  

 G3–G4

198 (52.1)

109 (57.4)

89 (46.8)

  
  1. FUSCC Fudan University Shanghai Cancer Center, BMI body mass index
  2. aThe AJCC staging system is a classification system developed by the American Joint Committee on Cancer for describing the extent of disease progression in cancer patients. It utilizes in part the TNM scoring system: Tumor size, Lymph Nodes affected, Metastases