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Table 1 Clinicopathological characteristics baseline in relation to AQP9 expression level in FUSCC cohort

From: Prognostic implications of Aquaporin 9 expression in clear cell renal cell carcinoma

Characteristics FUSCC cohort
(N = 380)
AQP9 expression χ2 p
High
(N = 190)
Low
(N = 190)
N (%)      
Age     0.296 0.587
 < 60 years 253 (66.6) 124 (65.3) 129 (67.9)   
 ≥ 60 years 127 (33.4) 66 (34.7) 61 (32.1)   
Gender     0.435 0.510
 Male 258 (67.9) 132 (69.5) 126 (66.3)   
 Female 122 (32.1) 58 (30.5) 64 (33.7)   
BMI     0.541 0.462
 < 25 kg/m2 231 (60.8) 112 (58.9) 119 (62.6)   
 ≥ 25 kg/m2 149 (39.2) 78 (41.1) 71 (37.4)   
pT stage     34.336 < 0.001
 T1–T2 307 (80.8) 131 (68.9) 176 (92.6)   
 T3–T4 73 (19.2) 59 (31.1) 14 (7.4)   
pN stage     14.246 < 0.001
 N0 334 (87.9) 155 (81.6) 179 (94.2)   
 N1 46 (12.1) 35 (18.4) 11 (5.8)   
pM stage     40.347 < 0.001
 M0 310 (81.6) 131 (68.9) 179 (94.2)   
 M1 70 (18.4) 59 (31.1) 11 (5.8)   
AJCC stagea     34.072 < 0.001
 I–II 292 (76.8) 122 (64.2) 170 (89.5)   
 III–IV 88 (23.2) 68 (35.8) 20 (10.5)   
ISUP grade     4.218 0.040
 G1–G2 182 (47.9) 81 (42.6) 101 (53.2)   
 G3–G4 198 (52.1) 109 (57.4) 89 (46.8)   
  1. FUSCC Fudan University Shanghai Cancer Center, BMI body mass index
  2. aThe AJCC staging system is a classification system developed by the American Joint Committee on Cancer for describing the extent of disease progression in cancer patients. It utilizes in part the TNM scoring system: Tumor size, Lymph Nodes affected, Metastases