Skip to main content

Advertisement

Springer Nature is making SARS-CoV-2 and COVID-19 research free. View research | View latest news | Sign up for updates

Table 8 Clinical characteristics of CRC involving the microbiological study

From: Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer

  Rectum group Sigmoid colon group p-value
Cases, n 15 13
Age (years) 59.53 ± 12.14 68.15 ± 9.75 0.051
Males, n 9 7 0.743
BMI (kg/m2) 22.96 ± 3.03 22.90 ± 2.91 0.956
Known hypertension, n 4 6 0.283
Known diabetes, n 2 0 0.172
Long-term Smoking history, n 3 3 0.843
Long-term drinking history, n 3 2 0.750
Red blood cells (1012/L) 4.38 ± 0.67 4.16 ± 0.51 0.336
Haemoglobin (g/L) 132.20 ± 21.55 124.69 ± 19.79 0.349
white blood cells (109/L) 5.53 ± 1.38 4.88 ± 1.38 0.225
Blood platelet (109/L) 228.73 ± 77.88 192.54 ± 52.56 0.168
Haematocrit 0.40 ± 0.06 0.40 ± 0.05 0.321
Mean red blood cell haemoglobin content 30.20 ± 1.90 29.65 ± 3.35 0.594
Mean corpuscular-haemoglobin concentration 331.40 ± 12.02 329.08 ± 13.85 0.639
Mean red blood cell volume 91.12 ± 5.27 89.90 ± 7.50 0.619
Red blood cell distribution width 12.78 ± 0.64 13.35 ± 2.12 0.332
Alanine transaminase (U/L) 15.97 ± 8.23 15.05 ± 5.40 0.732
Glutamic oxaloacetic transaminase (U/L) 18.93 ± 2.88 18.39 ± 2.18 0.585
Total protein (g/L) 66.19 ± 7.24 65.92 ± 5.39 0.910
Albumin (g/L) 37.78 ± 4.35 37.40 ± 3.86 0.810
Total bilirubin (g/L) 13.57 ± 7.79 13.00 ± 5.70 0.828
Direct bilirubin (g/L) 5.01 ± 2.62 4.60 ± 1.59 0.631
Creatinine (μmol/L) 70.61 ± 15.91 72.52 ± 15.60 0.753
Urea nitrogen (mmol/L) 5.56 ± 2.11 4.39 ± 1.43 0.101
Glucose (mmol/L) 5.13 ± 0.98 4.93 ± 0.60 0.536
CA125 10.31 ± 2.93 10.96 ± 3.17 0.579
CA153 8.09 ± 4.71 6.88 ± 3.26 0.444
CA724 2.21 ± 1.56 2.36 ± 2.20 0.843
CA199 9.12 ± 9.28 38.19 ± 50.70 0.038
CEA 19.62 ± 37.26 10.56 ± 15.23 0.421
Cytokeratin 19 fragment 1.61 ± 0.60 2.03 ± 0.84 0.137
Neuron specific enolase 11.69 ± 3.07 9.85 ± 2.09 0.102
Squamous cell carcinoma associated antigen 0.83 ± 0.59 0.73 ± 0.27 0.598
Alpha fetoprotein 3.20 ± 1.93 2.37 ± 0.74 0.154
Ki-67 (%) 61.33 ± 11.87 65.38 ± 13.91 0.413
TMN stage
 Stage II 13 8 0.126
 Stage III 2 5
  1. A total of 28 CRC patients including 15 cases of rectal cancer and 13 cases of sigmoid cancer in Huzhou Central Hospital from January 2018 to August 2018 were recruited in the microbiology and microbial metabolites study after screening and identification. Smoking and drinking history over the course of 1 year were recruited. The TMN stages are according to AJCC. Patient personal information, serological indicators, and Ki-67 indexes were collected from the hospital’s HIS system after the consent of the patients