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Table 3 Multivariate overall survival analysis of different clinical stages in CRC patients with different sites

From: Analysis of prognosis, genome, microbiome, and microbial metabolome in different sites of colorectal cancer

  Cecum Ascending colon
HR (95% CI)
Transverse colon
HR (95% CI)
Descending colon
HR (95% CI)
Sigmoid colon
HR (95% CI)
Rectum
HR (95% CI)
Stage at presentation
 Stage 0 1.00 0.77 (0.6–0.99)* 1.37 (0.96–1.96) 1.36 (1.01–1.83)* 1 (0.72–1.39) 1.07 (0.68–1.68)
 Stage I 1.00 0.72 (0.68–0.75)** 1.02 (0.95–1.09) 1.15 (1.08–1.21)** 1.07 (1.01–1.14)* 1.07 (0.98–1.16)
 Stage II 1.00 0.81 (0.78–0.84)** 0.92 (0.88–0.96)** 0.96 (0.93–1) 1.01 (0.97–1.05) 0.94 (0.89–0.99)*
 Stage III 1.00 0.63 (0.61–0.65)** 1 (0.96–1.04) 1.12 (1.08–1.16)** 1.05 (1.01–1.09)* 0.93 (0.88–0.97)*
 Stage IV 1.00 0.6 (0.58–0.62)** 0.94 (0.89–0.98)* 1.07 (1.03–1.11)* 0.95 (0.91–0.99)* 0.93 (0.89–0.98)*
 All stages 1.00 0.7 (0.69–0.71)** 0.95 (0.93–0.97)** 0.97 (0.95–0.99)* 1.04 (1.02–1.07)** 0.96 (0.93–0.98)*
  1. ** p < 0.001, *p < 0.05; CI confidence interval, HR hazard ratio. The classification criteria of stages refer to the AJCC/UICC TNM staging system. The cecum cancer group was set to 1 as the control group