Fig. 6

The network of a drug-gene interaction. The drug prediction databases DGIdb was used to predict drugs that interact with the differentially expressed genes in different sites of CRC. The Figure shows the network of drug-gene interaction. The yellow circles and purple circles represent the genes significantly associated with the ascending colon and the sigmoid colon, respectively. The white squares indicate predicted drugs. The red lines, green lines, and black lines represent the antagonistic effects, promoting effects, and unknown effects, respectively