Fig. 2

Effects of CD36 knockdown and overexpression on migration of cervical cancer cells in vitro. a, b Expression levels of CD36 in cervical cancer cell lines (**P < 0.01 vs. controls). c, d Three si-RNAs were selected to knockdown CD36 expression. Si-RNA-2 (si-2) was the most effective target sequence in our assay. e Expression levels of CD36 were significantly decreased by si-RNA (si-2) in SiHa and HeLa cells. f Expression level of CD36 was significantly enhanced after transfected with plasmid overexpressing CD36 in C33a cells. g–i Interference of CD36 expression inhibited migration both in SiHa and HeLa cells (*P < 0.05 vs. controls; **P < 0.01 vs. controls). g, j Enhancement of CD36 expression promoted migration of C33a cells (*P < 0.05 vs. controls)