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Table 2 Univariate and multivariate analyses for survival of squamous cell carcinoma patients
| Variables | Overall survival | Progression-free survival | ||
|---|---|---|---|---|
| HR (95% CI) | P | HR (95% CI) | P | |
| A (univariate) | ||||
| Gender | ||||
| Male | 1.50 (0.56–3.96) | 0.414 | 0.97 (0.42–2.25) | 0.954 |
| Female | 1 | 1 | ||
| Age (years) | ||||
| ≥ 60 | 0.47 (0.21–1.05) | 0.069 | 0.49 (0.23–1.04) | 0.065 |
| < 60 | 1 | 1 | ||
| Smoking status | ||||
| Ever smokers | 1.08 (0.46–2.56) | 0.852 | 0.81 (0.37–1.73) | 0.581 |
| Never smokers | 1 | 1 | ||
| cStage | ||||
| IV | 1.22 (0.58–2.56) | 0.597 | 1.15 (0.58–2.27) | 0.681 |
| III | 1 | 1 | ||
| Tumor differentiation | ||||
| Poor | 1.30 (0.58–2.91) | 0.52 | 1.29 (0.60–2.75) | 0.512 |
| Well/moderate | 1 | 1 | ||
| Performance status | ||||
| 1–2 | 1.72 (0.72–4.06) | 0.215 | 1.30 (0.63–2.68) | 0.471 |
| 0 | 1 | 1 | ||
| B | 1.29 (0.91–2.03) | 0.328 | 1.17 (0.96–1.82) | 0.532 |
| NK | 0.97 (0.57–1.82) | 0.165 | 0.92 (0.62–1.56) | 0.181 |
| NKT | 1.19 (0.73–1.65) | 0.720 | 1.21 (0.86–1.76) | 0.824 |
| γδT | 0.65 (0.35–1.36) | 0.611 | 0.78 (0.43–1.44) | 0.955 |
| CD8+CD28+ | 1.01 (0.94–1.10) | 0.749 | 0.99 (0.93–1.07) | 0.902 |
| CD8+CD28− | 2.01 (1.16–4.05) | 0.039 | 2.12 (1.07–4.36) | 0.023 |
| CD28+/CD28− | 0.96 (0.68–1.37) | 0.863 | 0.87 (0.61–1.22) | 0.414 |
| CD4+CD25hi | 1.17 (0.68–2.04) | 0.570 | 1.28 (0.78–2.10) | 0.331 |
| B (multivariate) | ||||
| Age (years) | 0.47 (0.21–1.05) | 0.064 | 0.48 (0.22–1.02) | 0.057 |
| CD8+CD28− | 1.41 (1.17–3.06) | 0.035 | 2.01 (1.06–3.85) | 0.029 |
