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Fig. 5 | Journal of Translational Medicine

Fig. 5

From: Mild hyperthermia by MR-guided focused ultrasound in an ex vivo model of osteolytic bone tumour: optimization of the spatio-temporal control of the delivered temperature

Fig. 5

Numerical simulation of the impulse response function of one osteolytic lesion, sonicated with the focal point symmetrically positioned in the center of the cortical breakthrough, axial bone diameter 12 mm. a Temperature elevation at the end of a short HIFU sonication isolating only the cortical source, followed by a free evolution of b 40 s and c 60 s. d Temperature elevation at the end of a short HIFU sonication considering the cumulated source of heating followed by a free evolution of e 40 s and f 60 s. Temperature color bar and graphical distance scale are provided

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