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Table 3 Echocardiographic parameters of the patients

From: Plasma concentration and expression of adipokines in epicardial and subcutaneous adipose tissue are associated with impaired left ventricular filling pattern

 

Controls

Obesity

Obesity + T2DM

EF (%)

47.7 ± 9.0

51.7 ± 9.7

53.4 ± 10.1

FS (%)

26.5 ± 7.7

33.2 ± 8.8

28.9 ± 7.1

TAPSE (mm)

25.9 ± 5.7

26.1 ± 4.1

24.0 ± 4.6

E/A

0.9 ± 0.3

0.8 ± 0.3

0.9 ± 0.4

DT (ms)

255.8 ± 86.9

227.6 ± 48.1

234.2 ± 64.7

IVRT (ms)

111.8 ± 21.2

107.9 ± 17.8

99.0 ± 19.6

E’ (cm/s)

8.0 ± 2.5

7.7 ± 1.7

7.0 ± 2.1

A’ (cm/s)

8.3 ± 1.9

8.7 ± 2.1

8.9 ± 1.5

DT’ (ms)

167.8 ± 63.3

165.5 ± 48.9

162.4 ± 57.3

E’/A’

1.1 ± 0.5

0.9 ± 0.3

0.8 ± 0.3

RVAC (mL)

43.9 ± 15.7

40.6 ± 9.5

39.8 ± 10.2

EATt (mm)

9.9 ± 2.2

12.1 ± 3.6

11.7 ± 2.9

LA (cm)

4.0 ± 0.4

4.1 ± 0.4

4.4 ± 0.5†

LVdD (cm)

5.4 ± 0.7

5.5 ± 0.5

5.4 ± 0.5

LVsD (cm)

3.9 ± 0.8

3.6 ± 0.6

3.9 ± 0.5

RVdD (cm)

2.4 ± 0.4

2.7 ± 0.4†

2.6 ± 0.4

IVSD (cm)

1.1 ± 0.2

1.1 ± 0.2

1.2 ± 0.2

PWTd (cm)

1.1 ± 0.1

1.1 ± 0.1

1.2 ± 0.2

RWT

0.4 ± 0.1

0.4 ± 0.1

0.4 ± 0.1

LVM (g)

226.8 ± 61.5

251.8 ± 58.6

260.0 ± 62.7

LVMi (g/m2.7)

52.9 ± 14.5

58.4 ± 11.8

59.9 ± 12.6

  1. EF ejection fraction, FS fractional shortening, TAPSE tricuspid annular plane systolic excursion, E/A the ratio of peak velocity blood flow in early diastole to peak velocity flow in late diastole, DT deceleration time of mitral inflow velocity, IVRT isovolumic relaxation time, E′ peak mitral annulus velocity in early diastole, A′ peak mitral annulus velocity in late diastole, DT′ deceleration time of the mitral annulus measured in tissue Doppler, RVAC right ventriculo-arterial coupling, EATt epicardial adipose tissue thickness, LA left atrium diameter, LVdD left ventricular end-diastolic diameter, LVsD left ventricular end-systolic diameter, RVdD right ventricular end-diastolic diameter, IVSD interventricular septum thickness, PWTd posterior wall thickness at end-diastole, RWT relative wall thickness, LVM left ventricular mass, LVMi left ventricular mass index
  2. †Indicates p < 0.05 as compared to non-obese controls