Table 3 Consistency between variant patterns in paired primary and metastatic lesions: A—classified (pathogenic/likely pathogenic and benign/likely benign) variants, B—all variants
Paired tissue types | No. of samples | Cases with consistent mutation pattern (%) | Cases with discrepant mutation pattern (%) |
|---|---|---|---|
A. Pathogenic/likely pathogenic + benign/likely benign variants | |||
 Primary vs. lymph node metastasis | 31 | 23 (74) | 8 (26) |
 Primary vs. visceral metastasis | 18 | 8 (44) | 10 (56) |
 Primary vs. metastasis | 49 | 31 (63) | 18 (37) |
B. All variants | |||
 Primary vs. lymph node metastasis | 31 | 9 (29) | 22 (71) |
 Primary vs. visceral metastasis | 18 | 3 (17) | 15 (83) |
 Primary vs. metastasis | 49 | 12 (24) | 37 (76) |