Table 3 Prediction models for the undifferentiated pleomorphic sarcoma cohort based on each type of splicing event
Risk score | Model | HR (95% CI) | p-value | ROC |
|---|---|---|---|---|
Risk score (AD) | ATP6AP1_90605_AD * 2.273 + DNAJB12_12092_AD * (− 0.121) + KLC1_29490_AD * (− 0.111) + LRIF1_4128_AD * (− 0.28) + RAI14_71719_AD * (− 5.893) | 5.742 (2.015–16.36) | 0.0011 | 0.756 |
Risk score (AP) | 6-Sep_89962_AP * (− 0.393) + ALKBH7_47027_AP * (− 0.255) + KIAA1217_10996_AP * 0.716 + UBR4_876_AP * 0.071 | 8.892 (2.951–26.80) | 0.0001 | 0.931 |
Risk score (AT) | GNPDA1_73859_AT * (− 8.763) + IL18BP_17471_AT * 0.073 + KLHL26_48496_AT * 0.155 | 5.391 (1.877–15.49) | 0.0018 | 0.843 |
Risk score (ES) | PARD3B_57099_ES * (− 0.448) + PDDC1_13757_ES * (− 1.314) + TMUB2_41797_ES * (− 0.193) | 4.690 (1.674–13.14) | 0.0033 | 0.669 |
Risk score (ME) | FYN_77273_ME * 0.128 + NDUFAF6_84594_ME * (− 0.059) | 3.170 (1.143–8.788) | 0.027 | 0.70 |
Risk score (RI) | ANKRD28_63628_RI * (− 0.917) + RAB43_66696_RI * (− 0.067) + ZNF773_52280_RI * 0.348 | 4.966 (1.739–14.18) | 0.0028 | 0.81 |
Risk score (merged) | ATP6AP1_90605_AD * 16.015 + UBR4_876_AP * (− 0.25) + GNPDA1_73859_AT * (− 120.044) + KLHL26_48496_AT * 2.08 | 3.780 (1.324–10.79) | 0.013 | 0.869 |