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Table 3 Expression of proteins related to the ATX–LPA axis according to histologic subtype of FC

From: Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors

Parameters Total
n = 111 (%)
Minimally invasive type
n = 61 (%)
Encapsulated angioinvasive type
n = 37 (%)
Widely invasive type
n = 13 (%)
p-value
ATX 0.296
 Negative 102 (91.9) 54 (88.5) 35 (94.6) 13 (100.0)  
 Positive 9 (8.1) 7 (11.5) 2 (5.4) 0 (0.0)  
LPA1 0.004
 Negative 73 (65.8) 32 (52.5) 31 (83.8) 10 (76.9)  
 Positive 38 (34.2) 29 (47.5) 6 (16.2) 3 (23.1)  
LPA2 0.987
 Negative 85 (76.6) 47 (77.0) 28 (75.7) 10 (76.9)  
 Positive 26 (23.4) 14 (23.0) 9 (24.3) 3 (23.1)  
LPA3 0.792
 Negative 52 (46.8) 27 (44.3) 19 (51.4) 6 (46.2)  
 Positive 59 (53.2) 34 (55.7) 18 (48.6) 7 (53.8)  
  1. Italic values represent significance of p-value (p < 0.05)