Table 3 Expression of proteins related to the ATX–LPA axis according to histologic subtype of FC
From: Expression of proteins related to autotaxin–lysophosphatidate signaling in thyroid tumors
Parameters | Total n = 111 (%) | Minimally invasive type n = 61 (%) | Encapsulated angioinvasive type n = 37 (%) | Widely invasive type n = 13 (%) | p-value |
|---|---|---|---|---|---|
ATX | 0.296 | ||||
Negative | 102 (91.9) | 54 (88.5) | 35 (94.6) | 13 (100.0) | |
Positive | 9 (8.1) | 7 (11.5) | 2 (5.4) | 0 (0.0) | |
LPA1 | 0.004 | ||||
Negative | 73 (65.8) | 32 (52.5) | 31 (83.8) | 10 (76.9) | |
Positive | 38 (34.2) | 29 (47.5) | 6 (16.2) | 3 (23.1) | |
LPA2 | 0.987 | ||||
Negative | 85 (76.6) | 47 (77.0) | 28 (75.7) | 10 (76.9) | |
Positive | 26 (23.4) | 14 (23.0) | 9 (24.3) | 3 (23.1) | |
LPA3 | 0.792 | ||||
Negative | 52 (46.8) | 27 (44.3) | 19 (51.4) | 6 (46.2) | |
Positive | 59 (53.2) | 34 (55.7) | 18 (48.6) | 7 (53.8) | |