Fig. 5
From: CDK4/6 inhibitor palbociclib suppresses IgE-mediated mast cell activation
Palbociclib suppression of ASA in vivo. a ASA model protocol (N = 5/group). Ketotifen treatment was as positive control. Palbociclib prevents ASA-induced reductions in body temperature b as well as ASA-induced increases in IL-10 (c) and IL-4 (d) serum levels in ASA mice (determined by ELISA). Means ± SDs of 3 independent experiments are shown; *p < 0.05, **p < 0.01 vs. control