Fig. 5

Down-regulation of collagen type III by SP-8356. a Representative image of collagen type III expression. Vehicle (n = 9) and SP-8356 (n = 9). Scale bars, 100 μm. Magnification, × 100. b Quantification of collagen type III expression. Data are presented as box plot ± range. ^**p < 0.01. c Representative image of α-smooth muscle-actin (α-SMA) expression. Vehicle (n = 9) and SP-8356 (n = 9). The nuclei were stained with DAPI. Scale bars, 100 μm. Magnification, × 100. (D) Quantification of α-SMA expression. Data are presented as box plot ± range. n.s.: not significant