Table 1 Ongoing major trials in stage III melanoma
From: New paradigm for stage III melanoma: from surgery to adjuvant treatment
Trial name | Trial ID | Aim |
|---|---|---|
Checkmate 915 | NCT03068455 | To determine whether nivolumab + ipilimumab, is more effective than nivolumab alone, in delaying recurrence in patients with complete surgical removal of stage IIIb/c/d or stage IV melanoma |
ECOG 1619 | NCT01274338 | To compare adjuvant ipilimumab with high-dose interferon alfa-2b in treating patients with high-risk stage III–IV melanoma that has been removed by surgery |
SWOG S1414 [27] | MCT02506153 | Randomized trial comparing standard of care to pembrolizumab in patients at high risk for recurrence and death after surgery |