Table 2 Effects of pentoxifylline (PTX, a cytokine blocker, 30 mg/kg, IP) treatment on metabolic and anatomic data in rats after HFD consumption for 17 weeks
Parameters | Control | Control + PTX | OH | OH + PTX |
|---|---|---|---|---|
BW (g) | 559 ± 41 | 548 ± 43 | 688 ± 51* | 645 ± 49 |
Plasma glucose (mg/dl) | 126 ± 12 | 122 ± 11 | 147 ± 16 | 142 ± 15 |
Plasma insulin (ng/ml) | 1.51 ± 0.3 | 1.48 ± 0.3 | 3.12 ± 0.31* | 2.09 ± 0.27# |
Plasma cholesterol (mg/dl) | 43.1 ± 4.1 | 42.0 ± 3.9 | 61.2 ± 6.5* | 58.3 ± 5.7 |
Plasma triglyceride (mg/dl) | 66.9 ± 6.6 | 65.8 ± 7.2 | 92.6 ± 9.3* | 85.2 ± 7.9 |
HW (mg) | 1609 ± 91 | 1610 ± 112 | 2218 ± 132* | 2021 ± 121 |
HW/BW (mg/g) | 2.91 ± 0.27 | 2.94 ± 0.35 | 3.22 ± 0.37 | 3.13 ± 0.40 |
Sum of WAT mass (g) | 28.5 ± 3.1 | 27.7 ± 3.3 | 63.6 ± 5.9* | 57.9 ± 4.2 |