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Fig. 4 | Journal of Translational Medicine

Fig. 4

From: Adipose afferent reflex is enhanced by TNFα in paraventricular nucleus through NADPH oxidase-dependent ROS generation in obesity-related hypertensive rats

Fig. 4

The effects of saline, R-7050 (TNFα receptor antagonist), DETC (superoxide dismutase inhibitor), PEG-SOD (superoxide scavenger) and Apo (NADPH oxidase inhibitor) pretreatment in the PVN on the AAR response to TNFα in the PVN. TNFα (1 ng) was administered 10 min after the pretreatment. The values are mean ± SD. For each group, n = 6–7; *p < 0.05 versus Saline + Saline; #p < 0.05 versus Saline + TNFα (1 ng); &p < 0.05 versus Control

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