Fig. 7

Functional tests (static and dynamic). a, b Static tests: MSCs and S-MSCs were significantly more effective than BMCs and vehicle to improve IDS. MSCs (red) and S-MSCs (violet) provided significantly higher ratios at day 28 in comparison with BMCs (blue). There was no difference between the MSCs and S-MSCs groups. c Dynamic test: S-MSCs, MSCs and BMCs were effective to restore a normal walk in comparison with vehicle [*comparison of MSCs group (n = 35) versus BMCs group (n = 40); ^#S-MSCs (n = 40) versus BMCs; ^¥S-MSCs versus MSCs; ^§BMCs versus vehicle (n = 20); ^ΔMSCs versus vehicle; ^∞S-MSCs versus vehicle]